Research

Antibody discovery and vaccine development research may be on the verge of rapidly expanding with data that previously took decades to acquire, thanks to LIBRA-seq, a new tool developed by Vanderbilt University researchers and their colleagues. Read More

A computational method that uses hospital billing codes and electronic health records can identify genetic disease cases before clinical teams do. Read More

Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions. Read More

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes. Read More

To explore how fear becomes entrenched, VUMC researchers traveled down the precise neuronal pathways in the brains of mice that trigger fear responses, and which normally extinguish the behaviors once the danger has passed. Read More

Researchers at VUMC have taken a major step that could ultimately facilitate development of a new class of antidepressants which may relieve symptoms more rapidly and effectively and with fewer side effects than current medications. Read More

Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit. Read More

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells. Read More

Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders. Read More

Understanding how RSV is transmitted, which strains dominate and how new strains emerge around the globe will guide better vaccine and anti-viral drug design. Read More

With $3.6 million in funding, researchers from the Vanderbilt University Institute of Imaging Science are developing a focused ultrasound neuromodulation device as a non-invasive and non-addictive method for treating chronic pain. Read More

The Oak Ridge National Laboratory collaboration with Vanderbilt University will grow stronger through a new faculty liaison—a School of Engineering professor—and enhanced management of travel assistance awards. Read More

A 25-member engineering team—13 seniors, 9 undergraduates and three graduate students—in the Vanderbilt Aerospace Design Laboratory is taking on the 2020 NASA Student Launch challenge.   Read More

A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults. Read More

In machine learning, generative adversarial networks (GANs) involve two artificial neural networks squaring off, one, the generator, trying to delude the other, the discriminator, into accepting synthetic data as real. Beyond their science and engineering applications, GANs can generate utterly convincing “photographs” of people who do not exist. Unrestricted use on a wide scale of... Read More

Simulated electronic health records could avoid patient privacy risks and help speed discovery. Read More

Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients. Read More

An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies. Read More

In a final five-minute flurry, MarmotE watched its lead slip. At the buzzer, the team placed second and won $1 million in the DARPA Spectrum Collaboration Challenge. The team of four researchers, now very close friends, have worked together since 2016 to create an AI-radio system that can manage the wireless spectrum, finding unused slices... Read More

An optical imaging technology developed by Orrin H. Ingram Professor of Biomedical Engineering Anita Mahadevan-Jansen and her group, in partnership with a medical device company, has been selected as a finalist for the 2019 R&D 100 Awards. Read More