NINDS

A protein in the myelin coating on nerves helps form a “seal” that enables effective nerve conduction; loss of the protein causes inherited neuropathies. Read More

Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception. Read More

Developmental biologist Chin Chiang, Ph.D., and his colleagues have discovered that Purkinje neurons in the cerebellum act as central regulators of neuronal development. Read More

Individuals with overexpression of the gene MECP2 have core features of autism spectrum disorder. Read More

The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system. Read More

Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex. Read More

When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects. Read More

Cells in the back of the developing brain can give rise to brain tumors, suggesting they may be a target for treatment. Read More

Understanding how mutations in neuronal receptors contribute to epilepsy could lead to improved therapies. Read More

Some patients may need a combo of medications to combat a condition that causes dizziness. Read More

Treatment with a drug used to prevent organ rejection partially reverses the course of tuberous sclerosis, research in mice suggests. Read More

Managing myocardial infarction – and the resulting heart failure – remains a clinical challenge. To search for chemicals that can stimulate cardiac muscle cell production, Vanderbilt Institute of Chemical Biology investigators led by Tao Zhong, Ph.D., Terri Ni, Ph.D., and Eric Rellinger, M.D., turned to a novel drug discovery tool:… Read More

Drug-like molecules described by Vanderbilt researchers could lead to Parkinson's treatments with fewer side effects. Read More

Vanderbilt University investigators have discovered surprising new insights into the actions of NSAIDs. Read More

A zebrafish model of the genetic disease tuberous sclerosis complex will speed new discoveries. Read More

Patients with certain autonomic nervous system disorders have impaired odor identification, which could aid in diagnosis. Read More