NIH
-
$5.2M NIH grant bolsters colorectal cancer research
Robert Coffey Jr., M.D., Ingram Professor of Cancer Research at Vanderbilt University, has received a five-year, $5.2 million grant from the National Institutes of Health (NIH) to study the role of extracellular RNA (ex-RNA) in colorectal cancer. Read MoreAug 15, 2013
-
Oxidative stress in autism
A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care. Read MoreAug 14, 2013
-
Noninvasive test detects stomach bug
A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer. Read MoreAug 12, 2013
-
‘Yo-yo dieting’ inflames fat tissue
Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone. Read MoreAug 9, 2013
-
Nuclear shield against cell death
The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold. Read MoreAug 8, 2013
-
Cognitive complaints, Alzheimer’s risk studied
A study of cognitive complaints in older adults showed that memory concerns from both the patient and an informant was most predictive of converting to Alzheimer’s disease or dementia within three years. Read MoreAug 1, 2013
-
Study explores race differences of lung cancer risk
Vanderbilt research scientist Melinda Aldrich, Ph.D., MPH, has been awarded a National Institutes of Health Academic Career Award to investigate some of the genetic secrets behind a greater risk of lung cancer among African-Americans compared with other racial and ethnic groups. Read MoreAug 1, 2013
-
Motor protein revs up cell division
A motor protein that helps drive cell division may be a promising new target for cancer therapeutics. Read MoreJul 29, 2013
-
Reducing fatal rhythms after heart attack
Reducing heart muscle response to calcium could decrease the risk of fatal arrhythmias after heart attacks. Read MoreJul 26, 2013
-
Visualizing data on network ‘maps’
The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification. Read MoreJul 25, 2013
-
Probing roles of a cell death protein
Vanderbilt researchers have discovered new roles for a protein involved in cell death processes that are activated to prevent tumor-causing DNA mutations. Read MoreJul 17, 2013
-
Defining patient retention
Vanderbilt researchers propose guidelines for defining patient retention in clinical studies – an important parameter that affects study conclusions and program evaluations. Read MoreJul 15, 2013
-
Methods for imaging myelin loss
Certain MRI metrics can be used to assess myelin loss in multiple sclerosis, which is important for planning and monitoring therapy. Read MoreJul 12, 2013
-
New tool helps research publications stay NIH-compliant
The National Institutes of Health requires scientists to provide public access to any peer-reviewed publications resulting from NIH-supported research through PubMed, the National Library of Medicine’s premier search system. Read MoreJul 11, 2013
-
Insights on glaucoma gene mutations
Glaucoma-causing mutations in the gene for myocilin reduce secretion of the protein into the aqueous humor, suggesting a new option for treatment. Read MoreJun 26, 2013
-
Predicting cancer’s response to therapy
Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding. Read MoreJun 24, 2013
-
Rhythm response tied to gene variant
A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder. Read MoreJun 21, 2013
-
Studies outline new model for staph bone infections
Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat. Read MoreJun 20, 2013
-
Disease linked to cell traffic jams
Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface. Read MoreJun 20, 2013
-
Not all reading disabilities are dyslexia
A common reading disorder goes undiagnosed until it becomes problematic, according to the results of five years of study performed by researchers at Peabody College of education and human development. Read MoreJun 14, 2013