NIH

The nuclear receptor TR3 contributes to ovarian cancer cell death in response to platinum-based chemotherapy – and may be a good target for overcoming cell resistance to certain treatments. Read More

Vanderbilt University may nominate one candidate for the 2014 Faculty Scholars Program. Read More

Vanderbilt may nominate one candidate for the Simons Investigators in the Mathematical Modeling of Living Systems (MMLS) award, which supports junior faculty for five years at $100,000 per year. Read More

Robert Coffey Jr., M.D., Ingram Professor of Cancer Research at Vanderbilt University, has received a five-year, $5.2 million grant from the National Institutes of Health (NIH) to study the role of extracellular RNA (ex-RNA) in colorectal cancer. Read More

A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care. Read More

A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer. Read More

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone. Read More

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold. Read More

A study of cognitive complaints in older adults showed that memory concerns from both the patient and an informant was most predictive of converting to Alzheimer’s disease or dementia within three years. Read More

Vanderbilt research scientist Melinda Aldrich, Ph.D., MPH, has been awarded a National Institutes of Health Academic Career Award to investigate some of the genetic secrets behind a greater risk of lung cancer among African-Americans compared with other racial and ethnic groups. Read More

A motor protein that helps drive cell division may be a promising new target for cancer therapeutics. Read More

Reducing heart muscle response to calcium could decrease the risk of fatal arrhythmias after heart attacks. Read More

The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification. Read More

Vanderbilt researchers have discovered new roles for a protein involved in cell death processes that are activated to prevent tumor-causing DNA mutations. Read More

Vanderbilt researchers propose guidelines for defining patient retention in clinical studies – an important parameter that affects study conclusions and program evaluations. Read More

Certain MRI metrics can be used to assess myelin loss in multiple sclerosis, which is important for planning and monitoring therapy. Read More

The National Institutes of Health requires scientists to provide public access to any peer-reviewed publications resulting from NIH-supported research through PubMed, the National Library of Medicine’s premier search system. Read More

Glaucoma-causing mutations in the gene for myocilin reduce secretion of the protein into the aqueous humor, suggesting a new option for treatment. Read More

Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding. Read More

A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder. Read More