NIH

Drugs that inhibit the Wnt signaling pathway can regenerate injured skin and may be useful in treating fibromatosis, degenerative joint disease and cancer. Read More

The irregular heart rhythm atrial fibrillation increases the risk of death in patients in the intensive care unit. Read More

Vanderbilt University School of Nursing (VUSN) has been awarded a four-year $660,633 grant from the National Institute of Health’s National Institute on Aging to study how psychophysical responses to acute experimental thermal pain differ between older adults with and without Alzheimer’s Disease (AD). Read More

The glutamine transporter protein appears to contribute to the survival of lung cancer cells, suggesting it may be a useful diagnostic biomarker and target for therapies. Read More

New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs. Read More

A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease. Read More

Infants diagnosed with drug withdrawal symptoms at birth, also known as neonatal abstinence syndrome (NAS), are nearly 2.5 times as likely to be readmitted to the hospital in the first month after being discharged compared with full-term infants born without complications, according to new Vanderbilt research released in the journal Hospital Pediatrics. Read More

A Vanderbilt study is showing that early intervention may be the key to stopping the depression cycle in families. Read More

To most effectively use electronic health records for research, investigators should query multiple components of the record to identify patients with specific diseases. Read More

Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory. Read More

A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack. Read More

The initial results of a landmark clinical trial sponsored by the National Institutes of Health (NIH) indicate lowering systolic blood pressure below a commonly recommended target significantly reduces rates of cardiovascular events and lowers risk of death in a group of adults 50 years and older. Read More

Eighteen-year-old Rachel Barnett of Robertson County is one of the first patients to be enrolled in the Undiagnosed Diseases Network (UDN) at Vanderbilt University Medical Center — one of seven medical centers around the country participating in a clinical research initiative of the National Institutes of Health to identify rare disorders in patients. Read More

Vanderbilt University researchers have received two major federal grants — totaling $7.6 million over four years — to support groundbreaking research aimed at making genetic information a routine part of patients’ electronic medical records. Read More

Choosing a career is like grading a diamond; you must consider your shortcomings, desires and values as well as your strengths, a biopharmaceutical company executive advised graduate students recently during a recent career conference at Vanderbilt University. Read More

Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer. Read More

Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases. Read More

Understanding how signaling molecules are transported within and out of the cell may help to uncover the causes of certain cancers. Read More

Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine. Read More

Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read More