NIH

An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations. Read More

Researchers at Vanderbilt University Medical Center have received more than $11 million in new grant support aimed at slowing the growing burden of diabetes. Read More

A team of Vanderbilt investigators developed a new method for rapidly generating heart muscle cells from stem cells. Read More

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States. Read More

Vanderbilt investigators have identified a new biomarker to assess platelet function. Read More

Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports. Read More

Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis. Read More

Thirty-three percent of pediatric heart transplant patients developed antibodies against the donor heart, which can lead to rejection, a new Vanderbilt study reports. Read More

Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution. Read More

Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer. Read More

Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell. Read More

Anne Kenworthy, Ph.D., professor of Molecular Physiology and Biophysics, has been named to a two-year term as chair of the Biochemistry and Biophysics of Membranes Study Section in the Center for Scientific Review of the National Institutes of Health (NIH). Read More

James Crowe Jr., M.D., director of the Vanderbilt Vaccine Center, and Anthony Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), recently participated in a U.S. Senate National Institutes of Health (NIH) caucus briefing held in Washington, D.C., by Senate NIH caucus co-chairs Sens. Lindsey Graham (R-SC) and Dick Durbin (D-IL). Read More

Use of opioid analgesics is associated with an increased risk of hospitalization for serious infections among patients with rheumatoid arthritis, according to a Vanderbilt study published in Arthritis & Rheumatology. Read More

The growth factor FGF1 induces the growth of new insulin-producing beta cells and may help treat type 2 diabetes. Read More

Treatment for congenital heart disease during infancy may result in cognitive and attentional deficits during adolescence and young adulthood, Vanderbilt researchers have found. Read More

A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells. Read More

Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery. Read More

Vanderbilt University scientists are a step closer to understanding how inflammation in the body can affect mood and behavior. Read More

Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections. Read More