NIH

A signaling protein overexpressed in upper gastrointestinal cancers is an attractive therapeutic target. Read More

New research from Vanderbilt University eavesdrops on gene expression in human immune system cells before and after vaccination against bird flu. Read More

Terrah Foster Akard is helping children facing serious and life-threatening illness create a digital record of their lives, and measuring the impact the practice has on their emotional wellbeing. Read More

Vanderbilt University Medical Center’s Division of Trauma, Emergency General Surgery and Surgical Critical Care was recently awarded two new research grants. Read More

Researchers at Vanderbilt University Medical Center (VUMC) have taken another step toward developing a vaccine against respiratory syncytial virus (RSV), the major cause of life-threatening pneumonia in infants worldwide. Read More

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection. Read More

Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions. Read More

Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance. Read More

An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered. Read More

Researchers at Vanderbilt have identified what may be a genetic “smoking gun” for autism spectrum disorder (ASD) — a mutation in the gene for the critical neuronal protein CaMKII. Read More

The research represents one of four Learning Disabilities Innovation Hubs established by the NIH in 2012. Read More

The health of people around the world depends to a large extent on the ability of the global health community to predict what challenges must be met in the future. Read More

High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells. Read More

“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity. Read More

The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response. Read More

Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways. Read More

The Vanderbilt Digestive Disease Research Center (VDDRC) celebrates its 15th anniversary this year with a third consecutive five-year renewal of its federal research grant. Read More

Integrins are membrane proteins made up of combinations of different “alpha” and “beta” subunits that enable cells throughout the body to interact with their surroundings. Read More

Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. Read More

Tumors cause the intracellular material surrounding them to stiffen. Softening this protective layer could make existing cancer treatments more effective, according to new research. Read More