NIH
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Structure of a stem cell niche
Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies. Read MoreFeb 28, 2018
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Cannabis compound reduces seizures
Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found. Read MoreFeb 26, 2018
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Competition announcement: 2018 NIH S10 Shared and High-End Instrumentation Grants
The National Institutes of Health has posted information for the 2018 S10 Shared and High-End Instrumentation Grants programs. These programs and links to their program announcements are: Shared Instrumentation Grant Program (SIG) (link is external): The SIG Program funds grant awards in… Read MoreFeb 22, 2018
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Mitochondrial mutations and disease
New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state. Read MoreFeb 22, 2018
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What’s On My Mind: America’s partnership with its research universities fuels our common future
The lasting impact of the historic partnership between the federal government and America's research universities is the topic of this week's column from Chancellor Nicholas S. Zeppos. Read MoreFeb 15, 2018
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A new target for neuroblastoma
Vanderbilt investigators have discovered that a sirtuin protein has oncogenic properties in neuroblastoma cells — and that blocking it reduces their growth and tumor-like characteristics. Read MoreFeb 14, 2018
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Cognition in rare hormonal disorder
Vanderbilt investigators have conducted the first systematic evaluation of cognitive function in children with a rare genetic disorder. Read MoreFeb 13, 2018
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Protecting transplanted lungs
Acetaminophen may offer a simple treatment to prevent tissue injury following lung transplant, Vanderbilt researchers have discovered. Read MoreFeb 12, 2018
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Muscular dystrophy clue
Vanderbilt investigators have discovered a role for immune system T cells in slowing the decline in skeletal muscle function in patients with Duchenne muscular dystrophy. Read MoreFeb 9, 2018
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Cell skeleton and the brush border
Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read MoreJan 31, 2018
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Imaging features predict tumor grade
Vanderbilt researchers have discovered imaging features associated with increased risk for aggressive meningiomas (tumors of the brain membranes) that could help guide surgical planning and patient counseling. Read MoreJan 29, 2018
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Versatile C. difficile blocker
New research reveals a unique mechanism of C. difficile toxin neutralization by a monoclonal antibody, suggesting new therapeutic approaches. Read MoreJan 26, 2018
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A cataract-heart connection
Studies of alpha-B crystallin in zebrafish could ultimately lead to improved treatment for cataracts and heart disease. Read MoreJan 25, 2018
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Number of minority trainees on rise, but not minority faculty
Vanderbilt investigators examined the entire training pathway of potential biomedical research faculty and found two key points of loss: during undergraduate education and in transition from postdoctoral fellowship to tenure-track faculty. Read MoreJan 25, 2018
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HDL and kidney injury after surgery
Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered. Read MoreJan 17, 2018
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A spicy finding
Vanderbilt researchers have discovered that curcumin — the active ingredient in the spice turmeric — needs to be metabolically activated to exert anti-inflammatory effects. Read MoreJan 16, 2018
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BOLD view of white matter
Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis. Read MoreJan 12, 2018
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Lighting up iron levels
A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease. Read MoreJan 11, 2018
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Vanderbilt signs licensing, research agreements to develop new approach to schizophrenia treatment
Under the terms of the licensing agreement, Lundbeck has exclusively licensed rights to compounds developed at Vanderbilt that act on a receptor in the brain that has been implicated in schizophrenia. Read MoreJan 8, 2018
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Asthma study may point to potential new therapeutic approach
New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition. Read MoreJan 4, 2018