NIH

D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics. Read More

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy. Read More

To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction. Read More

Vanderbilt neurologists have identified a protein modification that could be targeted to reduce neuronal excitability in epilepsy. Read More

A computational method that uses hospital billing codes and electronic health records can identify genetic disease cases before clinical teams do. Read More

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes. Read More

Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit. Read More

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells. Read More

A new continuum robot designed by Vanderbilt engineers achieves multiscale motion and may open up a huge world of previously impossible complex microsurgeries. Read More

Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders. Read More

Understanding how RSV is transmitted, which strains dominate and how new strains emerge around the globe will guide better vaccine and anti-viral drug design. Read More

With $3.6 million in funding, researchers from the Vanderbilt University Institute of Imaging Science are developing a focused ultrasound neuromodulation device as a non-invasive and non-addictive method for treating chronic pain. Read More

In machine learning, generative adversarial networks (GANs) involve two artificial neural networks squaring off, one, the generator, trying to delude the other, the discriminator, into accepting synthetic data as real. Beyond their science and engineering applications, GANs can generate utterly convincing “photographs” of people who do not exist. Unrestricted use on a wide scale of... Read More

Simulated electronic health records could avoid patient privacy risks and help speed discovery. Read More

Researchers at Vanderbilt's Biomolecular Multimodal Imaging Center are working to create a high-resolution, three-dimensional “atlas” of the human kidney that will help future researchers understand what exactly goes wrong when kidneys fail. Read More

An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies. Read More

Early detection of lymphedema, which occurs in 20% of patients following breast cancer treatment, may improve therapeutic options for patients. Read More

James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis. Read More

Researchers at Vanderbilt Peabody College received multiple grants from the U.S. Department of Education, the U.S. Department of Health and Human Services and the National Institutes of Health. Read More

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology. Read More