NCI
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Imaging probe for retinal disease
An imaging probe developed at Vanderbilt detects retinal inflammation early and may allow therapeutic intervention to prevent blindness. Read MoreOct 12, 2016
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BMI genotype and breast cancer risk
For breast cancer prevention, a new study provides evidence for lifestyle modification to reduce weight gain in adults. Read MoreSep 29, 2016
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Targeting norovirus “noxiousness”
New discoveries will guide efforts to develop vaccines or antiviral agents for norovirus, the most common cause of infectious diarrhea. Read MoreSep 28, 2016
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Restore T cells to fight leukemia
Modulation of T cell metabolism thus may represent a new therapeutic avenue for leukemia patients. Read MoreSep 14, 2016
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In search of new cancer targets
Vanderbilt researchers developed a new algorithm to find clinically targetable gene rearrangements in cancers. Read MoreSep 9, 2016
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New breast cancer driver
Vanderbilt investigators have demonstrated that a certain protein complex drives tumor progression in aggressive breast cancers. Read MoreAug 26, 2016
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Breast cancer: finding the smoking gun
A new method developed at Vanderbilt may help “inventory” all tumor-promoting genes. Read MoreJul 20, 2016
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VU takes key role in cancer drug discovery consortium
Vanderbilt University has been selected as one of seven Dedicated Centers in the nation for the next phase of the Chemical Biology Consortium (CBC), a national network of scientists on the leading edge of cancer drug discovery. Read MoreJun 23, 2016
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President nominates Hiebert for National Cancer Advisory Board
President Barack Obama has nominated Scott Hiebert, Ph.D., professor of Biochemistry and associate professor of Medicine, to serve as a member of the National Cancer Advisory Board (NCAB). Read MoreJun 21, 2016
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Pulmonary fibrosis culprits
New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease. Read MoreJun 6, 2016
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An Argonaute’s voyage to cancer
A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.” Read MoreApr 28, 2016
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Mechanism of a DNA repair protein
Vanderbilt investigators have discovered details about the mechanism of an important DNA repair protein that maintains genome stability. Read MoreApr 15, 2016
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Switching breast cancer off
Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets. Read MoreApr 14, 2016
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Pietenpol named to NCI Blue Ribbon Panel
Jennifer Pietenpol, Ph.D., B.F. Byrd Jr. Professor of Oncology and director of Vanderbilt-Ingram Cancer Center (VICC), has been selected to serve on a Blue Ribbon Panel that will inform the scientific direction and goals at the National Cancer Institute (NCI) for Vice President Joe Biden’s National Cancer Moonshot Initiative. Read MoreApr 7, 2016
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New role identified for p73 gene
The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility. Read MoreApr 1, 2016
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Cancer prevention and poverty
A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures. Read MoreMar 31, 2016
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ROCKs and cancer invasion
The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies. Read MoreMar 17, 2016
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Melanoma response to immune therapy
Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read MoreMar 3, 2016
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Combining treatments for melanoma
Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients. Read MoreFeb 18, 2016
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Overcoming lung cancer drug resistance
Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients. Read MoreFeb 10, 2016