NCI

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read More

Developmental biologist Chin Chiang, Ph.D., and his colleagues have discovered that Purkinje neurons in the cerebellum act as central regulators of neuronal development. Read More

The director of the National Cancer Institute, Harold Varmus, M.D., told an overflow crowd at this year’s Orrin Ingram Distinguished Lecture that he is concerned about the climate for discovery research in the United States. Read More

Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer. Read More

The director of the National Cancer Institute, Harold Varmus, M.D., will deliver the next Flexner Discovery Lecture on Thursday, Nov. 21. His lecture, “New Directions in Cancer Research,” will begin at 4 p.m. in 208 Light Hall. Read More

Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read More

Vanderbilt-Ingram Cancer Center’s Breast Specialized Program of Research Excellence (SPORE) has been awarded a third round of funding from the National Cancer Institute (NCI). Read More

David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes. Read More

Vanderbilt researchers have identified a key regulator of cell division. Read More

Magnesium and vitamin D appear to work together to reduce risk of death from cardiovascular disease and colorectal cancer. Read More

Understanding the regulation of mutant EGF receptors commonly found in lung cancers could lead to new targeted therapies. Read More

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer. Read More

Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug. Read More

Therapeutic nanoparticles may offer a powerful new way to image and treat cancer at the same time. Read More

Vanderbilt investigators have combined next-generation sequencing technologies and bioinformatics analyses to screen for genome-wide genetic mutations associated with drug resistance in a series of lung cancer cell lines. Read More

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies. Read More

The nuclear receptor TR3 contributes to ovarian cancer cell death in response to platinum-based chemotherapy – and may be a good target for overcoming cell resistance to certain treatments. Read More

A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer. Read More

A motor protein that helps drive cell division may be a promising new target for cancer therapeutics. Read More

The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification. Read More