NCI
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PET probe detects dying tumor cells
A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine. Read MoreMay 8, 2014
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Increased cell permeability may protect from colitis
Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation. Read MoreApr 25, 2014
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A new way to target cancer-driver Ras
Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way. Read MoreMar 13, 2014
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New direction for treating lung cancer
Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer. Read MoreFeb 7, 2014
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Human and Helicobacter co-evolution
by Denise Anthony (iStock) A Vanderbilt University-led research team has solved a long-standing riddle: Why do people of mostly Amerindian ancestry in the Andes have a gastric cancer rate that is 25 times higher than that of fellow Colombians of mostly African descent only 124 miles away on the coast?… Read MoreJan 23, 2014
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Moses to receive Vanderbilt Distinguished Alumni Award
Harold “Hal” Moses, the Hortense B. the Ingram Professor of Cancer Research at Vanderbilt University, is the recipient of the 2014 Distinguished Alumni Award — the highest honor for a member of the Vanderbilt alumni community. Read MoreJan 20, 2014
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Targeting tumor “supply lines”
A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies. Read MoreDec 18, 2013
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Therapeutic target for gastric cancer
A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read MoreDec 12, 2013
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VU study points to central regulator of neuron development
Developmental biologist Chin Chiang, Ph.D., and his colleagues have discovered that Purkinje neurons in the cerebellum act as central regulators of neuronal development. Read MoreDec 12, 2013
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Research climate must be enhanced: NCI director
The director of the National Cancer Institute, Harold Varmus, M.D., told an overflow crowd at this year’s Orrin Ingram Distinguished Lecture that he is concerned about the climate for discovery research in the United States. Read MoreDec 5, 2013
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Therapeutic target for synovial sarcoma
Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer. Read MoreNov 21, 2013
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National Cancer Institute director set for Discovery Lecture
The director of the National Cancer Institute, Harold Varmus, M.D., will deliver the next Flexner Discovery Lecture on Thursday, Nov. 21. His lecture, “New Directions in Cancer Research,” will begin at 4 p.m. in 208 Light Hall. Read MoreNov 14, 2013
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Molecular circuits in ovarian cancer
Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read MoreNov 13, 2013
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Breast SPORE lands NCI renewal
Vanderbilt-Ingram Cancer Center’s Breast Specialized Program of Research Excellence (SPORE) has been awarded a third round of funding from the National Cancer Institute (NCI). Read MoreNov 7, 2013
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VU study sheds new light on DNA replication
David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes. Read MoreNov 7, 2013
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Targets of SIN drive cell division
Vanderbilt researchers have identified a key regulator of cell division. Read MoreOct 25, 2013
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Magnesium impacts vitamin D status
Magnesium and vitamin D appear to work together to reduce risk of death from cardiovascular disease and colorectal cancer. Read MoreOct 14, 2013
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Probing mutant EGF receptor regulation
Understanding the regulation of mutant EGF receptors commonly found in lung cancers could lead to new targeted therapies. Read MoreOct 10, 2013
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Cell changes en route to stomach cancer
Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer. Read MoreSep 26, 2013
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Fishing for new anti-cancer drugs
Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug. Read MoreSep 18, 2013