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Matthew Tyska Archives

How microvilli form

Sep. 21, 2018—Research led by Matthew Tyska gives new insight into the formation of the lining of the gut that helps us absorb nutrients and guard against illness.

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Cell skeleton and the brush border

Jan. 31, 2018—Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines.

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Celebration honors 11 new endowed chair holders

Dec. 5, 2017—Eleven Vanderbilt University faculty members named to endowed chairs were recognized for their outstanding scholarship and research during a celebration at the Student Life Center Nov. 29.

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Motoring to the tips of the brush border

Oct. 6, 2016—New findings implicate a motor protein in the assembly of the brush border in the intestines and kidneys – a specialized surface that is critical for healthy organ function.

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Building intestinal brush borders

Feb. 8, 2016—Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease.

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Faculty meeting highlights VUSM achievements

May. 29, 2014—Despite a challenging health care landscape, Vanderbilt University Medical Center continues to advance the highest-quality patient care, train the next generation of physician leaders and push forward the frontiers of biomedical science.

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Nutrient-absorbing surface’s assembly revealed: study

Apr. 17, 2014—Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.

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New ‘super’ microscopes sharpen cellular imaging

Jul. 11, 2013—Two new “super-resolution” optical microscopes have put Vanderbilt University Medical Center on the cutting edge of cellular imaging, and are giving researchers their first views of the cell at the molecular level.

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Intestinal artillery launches anti-bacterial attack

May. 14, 2012—The epithelial cells that line the intestines have a newly discovered mechanism for protecting us against microbes: they fire anti-bacterial "bullets" into the gut.

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