Matthew Tyska
Team set to study undiagnosed congenital diarrhea in infants
Oct. 24, 2019—Researchers at four institutions, including Vanderbilt, have been awarded a five-year, $9.4 million federal grant to tackle undiagnosed congenital diarrheas caused by a single gene mutation.
Microvilli in motion
Sep. 19, 2019—Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.
Adhesion protein optimizes border
Feb. 15, 2019—Matthew Tyska and colleagues have found that an adhesion protein in the gut is necessary for proper intestinal functioning.
How microvilli form
Sep. 21, 2018—Research led by Matthew Tyska gives new insight into the formation of the lining of the gut that helps us absorb nutrients and guard against illness.
Up Close and Personal: Vanderbilt explores the frontiers of imaging technology
Jun. 8, 2018—Recent advances in imaging technology are enabling Vanderbilt scientists to gain unprecedented views of how molecules, cells and tissues work together, yielding radical new insights into the causes, treatment and prevention of disease.
Cell skeleton and the brush border
Jan. 31, 2018—Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines.
Celebration honors 11 new endowed chair holders
Dec. 5, 2017—Eleven Vanderbilt University faculty members named to endowed chairs were recognized for their outstanding scholarship and research during a celebration at the Student Life Center Nov. 29.
Motoring to the tips of the brush border
Oct. 6, 2016—New findings implicate a motor protein in the assembly of the brush border in the intestines and kidneys – a specialized surface that is critical for healthy organ function.
Building intestinal brush borders
Feb. 8, 2016—Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease.
Faculty meeting highlights VUSM achievements
May. 29, 2014—Despite a challenging health care landscape, Vanderbilt University Medical Center continues to advance the highest-quality patient care, train the next generation of physician leaders and push forward the frontiers of biomedical science.
Nutrient-absorbing surface’s assembly revealed: study
Apr. 17, 2014—Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.
New ‘super’ microscopes sharpen cellular imaging
Jul. 11, 2013—Two new “super-resolution” optical microscopes have put Vanderbilt University Medical Center on the cutting edge of cellular imaging, and are giving researchers their first views of the cell at the molecular level.