James Crowe
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16 faculty members honored at Fall Faculty Assembly
Chancellor Daniel Diermeier and Faculty Senate Chair Catherine McTamaney presented faculty awards for both spring and fall 2020 as part of the virtual faculty assembly held Aug. 27. Read MoreAug 28, 2020
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Antibody research at Vanderbilt University Medical Center shows promise in fight against COVID-19
Based on positive results in preclinical studies reported today, potently neutralizing antibodies identified by researchers at Vanderbilt University Medical Center are showing promise as a potential therapy for preventing and treating COVID-19. Read MoreJul 15, 2020
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Research team isolates antibodies that may prevent rare polio-like illness in children linked to a respiratory infection
Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection. Read MoreJul 3, 2020
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The Front Lines: Vanderbilt physicians, researchers join worldwide fight against COVID-19
From the front lines of patient care to collaborating with scientists across the globe searching for treatments and vaccines, Vanderbilt University Medical Center and Vanderbilt University researchers have been working for months to combat the COVID-19 pandemic. Read MoreMay 14, 2020
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Antibodies eye Pacific Island “fever”
Vanderbilt Vaccine Center team isolates monoclonal antibodies against the mosquito-borne Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months. Read MoreMay 14, 2020
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Antibody finding raises hopes for Marburg, COVID-19 treatments
Monoclonal antibodies against Marburg virus — a more lethal cousin of the RNA virus that causes COVID-19 — may aid in the development of antibody "cocktails" to counter viral infection. Read MoreApr 30, 2020
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Vanderbilt University Medical Center and AstraZeneca join forces to identify potential COVID-19 treatments
Vanderbilt University Medical Center and the global biopharmaceutical company AstraZeneca have joined forces to identify candidates for antibody-based treatments that could protect people exposed to the 2019 novel coronavirus disease, COVID-19. Read MoreApr 9, 2020
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Researchers developing potential coronavirus antibody therapies
Vanderbilt University Medical Center is teaming up with academic, governmental and corporate partners in an unprecedented, fast-tracked global effort to develop antibody-based treatments to protect people exposed to the 2019 novel coronavirus disease, COVID-19. Read MoreApr 8, 2020
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VUMC-led team isolates antibody that blocks bird flu
VUMC scientists are redoubling their efforts to help people fight off bird flu. Their focus is H7N9, one of the most dangerous of the influenza viruses that have been transmitted from birds to humans. Read MoreDec 12, 2019
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Flu’s “hidden target” may lead to universal vaccine: study
The flu mutates so quickly that we need a new vaccine every year, but Vanderbilt scientists have found a vulnerable part of the virus that doesn't mutate as much. Read MoreMay 16, 2019
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VUMC chikungunya antibody set to enter clinical trial
A monoclonal antibody against the chikungunya virus developed by researchers at Vanderbilt University Medical Center is the first monoclonal antibody encoded by messenger RNA to enter a clinical trial. Read MoreFeb 21, 2019
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Researchers push forward frontiers of vaccine science
Using sophisticated gene sequencing and computing techniques, Vanderbilt researchers have achieved a first-of-its-kind glimpse into how the body’s immune system gears up to fight off infection. Read MoreFeb 13, 2019
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Designing antibodies to fight the flu
James Crowe Jr. and colleagues have developed a new computational method that may allow researchers to develop flu antibodies that can protect against more strains of the disease. Read MoreJan 31, 2019
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VUMC scientists ‘sprint’ to find anti-Zika antibodies
Scientists at Vanderbilt University Medical Center and colleagues in Boston, Seattle and St. Louis are racing to develop — in a mere 90 days — a protective antibody-based treatment that can stop the spread of the Zika virus. Read MoreJan 25, 2019
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Research explores link between stem cell transplant, diabetes
Brian Engelhardt is studying why as many as 50 percent of stem cell transplant recipients develop diabetes. Read MoreJan 17, 2019
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Discovery could lead to neutralizing West Nile virus
Research led by James Crowe, Jr., could lead to the first effective treatment for this dangerous mosquito-transmitted infection. Read MoreDec 7, 2018
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Team isolates antibodies that neutralize GI bug norovirus
The discovery of these antibodies could significantly improve the diagnosis and treatment of the leading cause of stomach illness in the world. Read MoreAug 30, 2018
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New target to stop Ebola
A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members. Read MoreMay 21, 2018
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Alphavirus “Achilles heel”
Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses. Read MoreMay 17, 2018
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Hope for an RSV vaccine
Newly discovered features in an RSV protein may be useful for rational structure-based vaccine design. Read MoreFeb 23, 2018