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Study finds genetic clues to pneumonia risk and COVID-19 disparities
Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. Read MoreJan 21, 2021
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NIH grant bolsters research on heart disease, cholesterol
Thanks to major funding from the National Institutes of Health (NIH), researchers at Vanderbilt University Medical Center have made major inroads in understanding how high-density lipoprotein (HDL), commonly known as good cholesterol, in some cases may... Read MoreJan 21, 2021
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Inflammation in genetic epilepsy
Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments. Read MoreJan 21, 2021
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WIN for blocking cancer growth
William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth. Read MoreJan 21, 2021
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Optical computing at sub-picosecond speeds developed at Vanderbilt
Vanderbilt researchers have developed the next generation of ultrafast data transmission that may make it possible to make already high-performance computing “on demand.” The technology unjams bottlenecks in data streams using a hybrid silicon-vanadium dioxide waveguide that can turn light on and off in less than one trillionth of a second. The article, “Sub‐Picosecond Response... Read MoreJan 19, 2021
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Bick selected as first VUMC Discovery Scholar in Health and Medicine
Alexander Bick, MD, PhD, assistant professor of Medicine in the Division of Genetic Medicine at Vanderbilt University Medical Center, has been selected as the first VUMC Discovery Scholar in Health and Medicine. Read MoreJan 14, 2021
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Mitochondrial stress and hypertension
Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential. Read MoreJan 12, 2021
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Microbial RNA and rheumatoid arthritis
Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases. Read MoreJan 11, 2021
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Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients
COVID-19 patients admitted to intensive care in the early months of the pandemic were subject to a significantly higher burden of delirium and coma than is typically found in patients with acute respiratory failure. Read MoreJan 8, 2021
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Brunger leads $1.5 million NSF project to develop advanced brain organoids
Vanderbilt engineers have received a $1.49 million National Science Foundation grant to advance the science of organoids with cells that organize themselves and mimic the development of human brain structures. Read MoreJan 7, 2021
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Functional seizures associated with stroke, psychiatric disorders in electronic health records study
In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them. Read MoreJan 7, 2021
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Vitamin D activation and cancer risk
Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women. Read MoreJan 7, 2021
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Building a cohort, the easy way
An automated system using keyword searches can help identify candidates for clinical trials on adverse drug reactions. Read MoreJan 7, 2021
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Genome editing technique “rescues” mice from accelerated aging disorder: study
Researchers from the Broad Institute of Harvard and MIT, the National Institutes of Health (NIH) and Vanderbilt University Medical Center for the first time have used a novel genome-editing technique to “rescue” mice from progeria, a rare genetic disease that causes accelerated aging. Read MoreJan 6, 2021
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Vanderbilt civil engineer partners with TDOT to seek ways to mitigate opioid epidemic
One of the largest obstacles for patients seeking effective substance abuse treatment is a lack of transportation to the treatment facilities. Vanderbilt University researcher Janey Camp, associate professor of civil and environmental engineering, is working on a project to help clear those roadblocks. Janey Camp (Vanderbilt University) Camp is leading an 18-month, in-depth analysis of... Read MoreJan 6, 2021
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VUMC, Case Western apply artificial intelligence to “customize” oral cancer treatment
Researchers at Vanderbilt University Medical Center and Case Western Reserve University in Cleveland have been awarded a five-year, $3.3 million grant by the National Cancer Institute to apply artificial intelligence (AI) to help customize treatment for oral cancer patients. Read MoreJan 5, 2021
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Study reveals distinct genomic landscape for young adults with appendiceal cancer
The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances. Read MoreDec 17, 2020
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Study reveals new strategy for reducing tumor growth, metastasis
A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma. Read MoreDec 17, 2020
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COVID-associated delays for elective services studied
This spring in the U.S., there were widespread delays in elective health care procedures and screenings. Read MoreDec 17, 2020
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Health equity’s role in pandemic response crucial
In March, Vanderbilt University Medical Center leaders established a command center on campus to address the myriad issues that the Medical Center would face in the coming days, weeks and months as the COVID-19 pandemic encroached on Tennessee, then Nashville and finally on campus. Read MoreDec 16, 2020