Health And Medicine

Aviv Regev, PhD, an internationally known computational biologist and executive vice president of Genentech Research and Early Development (gRED), is the recipient of the 2021 Vanderbilt Prize in Biomedical Science, officials at Vanderbilt University Medical Center announced this week. Read More

Using primary cells from patients with chronic myelomonocytic leukemia, Vanderbilt researchers found synergistic inhibition of cell viability and proliferation, suggesting a new treatment strategy. Read More

Vanderbilt University Medical Center (VUMC) has been named Data Coordinating Center (DCC) for a nationwide platform of studies aimed at “repurposing” existing drugs to treat mild to moderate symptoms of COVID-19. Read More

A switch to paper forms during the COVID-19 pandemic might have hobbled research, but using software with a novel user interface made it possible to accurately extract information from scanned forms. Read More

Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function. Read More

Charles Sanders, PhD, and colleagues show how a “supertrafficking” mutant potassium channel contributes to heart rhythm abnormalities. Read More

Cancer specialists at Vanderbilt University Medical Center, in partnership with biochemists and structural biologists across the Vanderbilt University campus, are taking “personalized” cancer therapy to a new level. Read More

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years. Read More

Unique somatic gene mutations may contribute to racial disparities in the incidence of Wilms tumor — the most common childhood kidney cancer. Read More

Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine. Read More

Team members serving COVID-19 inpatients were more densely connected, interacting far more than their medical ICU counterparts. Read More

The discovery of monoclonal antibodies that neutralize Rift Valley Fever Virus — an emerging infection with pandemic potential — lays the foundation for future therapeutic antibody development. Read More

Despite an impressive vaccination effort that exceeds 2 million shots a day, rates of COVID-19 are again on the rise in several parts of the United States, as is the spread of highly transmissible variants of the virus. Read More

Vanderbilt’s Muktar Aliyu, MBBS, MPH, DrPH, and Hilary Tindle, MD, MPH, will be inducted this year into the American Society for Clinical Investigation (ASCI), an elite honor society of physician-scientists from the upper ranks of academic medicine and industry. Read More

Richard Tsien, PhD, director of the Neuroscience Institute at NYU Langone Medical Center, will deliver the next web-based Discovery Lecture. Read More

An FDA-approved medication enhances the function of T regulatory cells (Treg), a class of immune cells that restrains the immune response, Vanderbilt investigators have discovered. Read More

Distinct cancer-associated fibroblasts in the prostate tumor microenvironment may influence tumor progression and could point to new therapeutic targets. Read More

Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people. Read More

High-intensity strength training is not more effective than low-intensity training or educational efforts for reducing knee pain in patients with osteoarthritis. Read More

In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes. Read More