Health And Medicine
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Better adenoma detection
Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans. Read MoreMay 4, 2023
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Study details RNA editing in virus-infected cancer cells
Vanderbilt researchers detail the landscape of RNA editing — a form of RNA modification — in primary effusion lymphoma cells during Kaposi’s sarcoma-associated herpesvirus infection and identify an edited viral microRNA that is critical for infection. Read MoreApr 20, 2023
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Low-professionalism residents later draw higher patient complaints: study
A Vanderbilt study finds a strong association between lower ratings for interpersonal communication skills among medical residents in their last year of training and greater likelihood of unsolicited patient complaints among doctors during their first year of employment after training. Read MoreApr 13, 2023
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Research identifies new target that may prevent blood cancer
An international coalition of biomedical researchers co-led by Vanderbilt's Alexander Bick, MD, PhD, has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients’ risk of blood cancer. Read MoreApr 12, 2023
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VUMC-led trial shows two investigational drugs are ineffective for treating severe COVID-19
A Vanderbilt-led study evaluating two investigational drugs to treat severe COVID-19 demonstrated that neither drug was effective. Read MoreApr 11, 2023
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Mathers Foundation award supports study of bacterial physiology
Vanderbilt's Wenhan Zhu, PhD, has received a three-year award from the G. Harold and Leila Y. Mathers Foundation to support his research that aims to answer a fundamental question about bacterial physiology and engineer probiotics to improve gut inflammatory diseases. Read MoreMar 23, 2023
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Scientists resurrect a ‘dead’ antibody to study protein
Vanderbilt was part of a multi-center team that resurrected a “dead antibody” to reveal the mysteries of cytochrome c, a versatile protein that is an essential part of the cell’s energy-generating capacity, and of life itself. Read MoreMar 16, 2023
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Study evaluates polygenic risk score for prostate cancer risk prediction
A Vanderbilt study found that prostate cancer polygenic risk score has limited utility for enhancing prostate cancer screening. Read MoreMar 16, 2023
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Study finds RSV may evade vaccines via rapid mutation
A Vanderbilt study concluded that RSV’s ability to mutate rapidly to escape detection by the body’s immune system makes it more challenging to design and develop vaccines that can stop it from spreading. Read MoreMar 9, 2023
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Study finds chronically disrupted sleep may increase risk for heart disease
Vanderbilt research found that sleep irregularity — chronically disrupted sleep and highly variable sleep durations night after night — may increase the risk for atherosclerosis. Read MoreFeb 15, 2023
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Team’s imaging strategy enhances lipedema treatment
A collaborative team at Vanderbilt is transforming the diagnosis and treatment of lipedema, a debilitating, abnormal deposition of fatty tissue that afflicts an estimated 17 million women in the United States. Read MoreFeb 9, 2023
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Researchers clarify role of blood cell mutations in disease
Vanderbilt researchers have developed a new method to analyze mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells. Read MoreFeb 2, 2023
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Study reveals new genetic disorder that causes susceptibility to opportunistic infections
An international consortium co-led by Vanderbilt's Rubén Martínez-Barricarte has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia. Read MoreJan 20, 2023
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VUMC researchers upend dogma about vasopressin production
Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney. Read MoreJan 5, 2023
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Novel therapeutic target identified for chronic kidney disease
Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury. Read MoreDec 15, 2022
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Reduced kidney function may cause cardiovascular disease: study
An international team of investigators has found that mild to moderate reduction in kidney function may cause cardiovascular disease, even in people without symptoms of heart disease or diabetes. Read MoreDec 15, 2022
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Study links excess oxygen during anesthesia to risk of organ injury
A Vanderbilt study found that higher levels of excess oxygen given to patients under general anesthesia add risk of injury to the kidneys, lungs and heart. Read MoreNov 30, 2022
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Study supports removing race from estimate of kidney function
An in-depth analysis by Vanderbilt investigators of published research studies supports removing race from the calculation of estimated glomerular filtration rate (eGFR) — an assessment of kidney function. Read MoreNov 17, 2022
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Cardiac antigen identified as mechanism for heart complication with immunotherapy-related myocarditis
Researchers from from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation myocarditis. Read MoreNov 16, 2022
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Hawiger still blazing a trail in inflammation research
Vanderbilt research describes a new investigational peptide drug that can penetrate immune and nonimmune cells, and block inflammatory signaling in a preclinical model of atopic dermatitis — eczema. Read MoreNov 10, 2022