Health And Medicine
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Molecular ‘switch’ may illuminate stomach disorders
An international team that included researchers from Vanderbilt University Medical Center has discovered a molecular switch that induces rapid proliferation of zymogen granule-secreting chief cells in the stomach to regenerate damaged tissue. Read MoreMay 19, 2022
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Study identifies first cellular “chaperone” for zinc, sheds light on worldwide public health problem of zinc deficiency
A team led by Vanderbilt researchers has described and characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins. Read MoreMay 17, 2022
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Study sheds light on the dark side of obesity
Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity. Read MoreMay 12, 2022
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VUMC-led study finds Moderna COVID vaccine safe and effective for children
Moderna’s COVID-19 vaccine is safe and generates robust immune responses in children ages 6 to 11 years, a national clinical trial co-led by C. Buddy Creech, MD, MPH, has found. Read MoreMay 12, 2022
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Resistance to COVID-19 drug detected in lab study
Vanderbilt research shows that the virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism. Read MoreMay 10, 2022
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VUMC team discovers how bacterial pathogen survives without water
Vanderbilt researchers are studying a bacterial pathogen that can survive on hospital surfaces — without water — for months, an ability that has helped it become a leading cause of hospital-acquired infections. Read MoreMay 5, 2022
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Studies combine genetic testing, electronic health records to find undiagnosed diseases
Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations. Read MoreApr 28, 2022
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Study advances understanding of bacterial bioterrorism agent
Vanderbilt researchers have identified a critical regulatory factor in the bacterium that causes the disease anthrax and has been used as a biological weapon. Read MoreApr 7, 2022
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High blood pressure genes improve heart surgery survival in children
Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery. Read MoreMar 24, 2022
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Probing cancer cell invasion
The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells. Read MoreMar 1, 2022
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Invasive strep can defy zinc toxicity
Vanderbilt researchers find that invasive Group B Streptococcus strains, a significant risk to pregnant patients and infants, can grow in presence of toxic zinc levels. Read MoreFeb 28, 2022
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PET imaging probe for Alzheimer’s disease
Vanderbilt researchers report on a new PET imaging probe that will be useful for exploring Alzheimer’s disease pathology. Read MoreFeb 24, 2022
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Predicting brain cancer outcome
Red blood cell distribution width has prognostic value for many diseases, but it was not associated with overall survival in patients with glioblastoma, Vanderbilt researchers found. Read MoreFeb 15, 2022
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Diverticulitis surgery: guidelines needed
Surgical removal of the colon for recurrent diverticulosis varies by geographic region and is associated with surgeon and hospital factors; stronger national guidelines are needed, Vanderbilt researchers report. Read MoreFeb 10, 2022
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Gene variants increase risk of kidney failure in Black veterans with COVID-19: study
Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19. Read MoreFeb 10, 2022
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VUMC study raises hope for improving treatment of kidney disease
Vanderbilt research has revealed an important mechanism in the kidney by which a cell surface receptor known as DDR1 fans the flames of inflammation and fibrosis that ultimately lead to kidney failure. Read MoreFeb 2, 2022
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Accelerating podocyte production
A new method developed by Vanderbilt researchers to generate kidney cells from stem cells offers a faster and less expensive way to make these valuable tools for studying kidney diseases. Read MoreFeb 1, 2022
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Impact of digital health interventions
Vanderbilt researchers test and recommend statistical approaches to study the association between engagement with digital health interventions and clinical outcomes. Read MoreJan 31, 2022
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White matter and psychosis
The microstructure of white matter in the brain could be an important risk marker for psychosis, Vanderbilt researchers have discovered. Read MoreJan 27, 2022
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Impaired neutrophils in autoimmunity
Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. Read MoreJan 27, 2022