Department Of Pediatrics

Geoffrey Fleming, professor of pediatrics in the Division of Pediatric Critical Care Medicine and vice president of Vanderbilt University Medical Center Continuous Professional Development, died Dec. 8. He was 50. Fleming was diagnosed with metastatic cholangiocarcinoma in August 2019. Read More

The isolation of human monoclonal antibodies against dangerous viruses including EEEV, Hendra and Nipah could offer new ways to treat and prevent these infections. Read More

Diabetes drugs known as GLP-1 receptor agonists, such as exenatide (Byetta), are a promising and safe treatment for a rare form of obesity. Read More

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found. Read More

Physician-scientists at Vanderbilt University Medical Center are investigating whether SARS-CoV-2, the virus that causes COVID-19, can be spread through aerosolized emissions (microscopic droplets and particles) during minimally invasive surgery in children. Read More

Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines. Read More

Vanderbilt researchers conducted the largest analysis to date of a heart complication in children following stem cell transplant. The findings may help guide screening practices to improve outcomes. Read More

An experimental coronavirus vaccine stimulated robust immune responses against SARS-CoV-2, the virus that causes COVID-19, and raised no serious safety concerns in an early-stage clinical trial. Read More

This week researchers at Vanderbilt University Medical Center (VUMC), the University of North Carolina at Chapel Hill and Gilead Sciences reported that remdesivir potently inhibited SARS-CoV-2, the virus which causes COVID-19, in human lung cell cultures and that it improved lung function in mice infected with the virus. Read More

The investigational antiviral drug remdesivir can shorten the time to recovery in adults hospitalized with COVID-19, according to preliminary results of a clinical trial published last month in The New England Journal of Medicine. Read More

Vanderbilt Vaccine Center team isolates monoclonal antibodies against the mosquito-borne Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months. Read More

Monoclonal antibodies against Marburg virus — a more lethal cousin of the RNA virus that causes COVID-19 — may aid in the development of antibody "cocktails" to counter viral infection. Read More

Parents of children with autism spectrum disorders benefited from the addition of mindfulness-based stress reduction to parent-implemented behavioral interventions. Read More

Vanderbilt University Medical Center and the global biopharmaceutical company AstraZeneca have joined forces to identify candidates for antibody-based treatments that could protect people exposed to the 2019 novel coronavirus disease, COVID-19. Read More

Researchers at Vanderbilt University Medical Center are playing a key role in the development of a potential new antiviral drug to treat COVID-19. Read More

Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth. Read More

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered. Read More

Understanding how RSV is transmitted, which strains dominate and how new strains emerge around the globe will guide better vaccine and anti-viral drug design. Read More

For patients in pediatric intensive care who are at high risk for acute kidney injury (AKI), giving clinicians automated decision support during the electronic order entry process increased the rate of blood testing for AKI by 9%. Read More

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease. Read More