Department Of Medicine

Post-transplantation diabetes mellitus (PTDM), a common complication of immunosuppressive drugs that are given to prevent transplant rejection, may be reversible and at least partially preventable, researchers at VUMC report. Read More

Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer. Read More

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered. Read More

Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy. Read More

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms. Read More

To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction. Read More

A computational method that uses hospital billing codes and electronic health records can identify genetic disease cases before clinical teams do. Read More

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes. Read More

Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit. Read More

Understanding how RSV is transmitted, which strains dominate and how new strains emerge around the globe will guide better vaccine and anti-viral drug design. Read More

A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults. Read More

Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients. Read More

The Department of Medicine will host a mini-retreat exploring “The Janus Face of Immunotherapy: The Good, the Bad, the Weird” on Friday, Nov. 1, led by Dr. Javid Moslehi and Dr. Doug Johnson. The event will be from 11:30 a.m. to 4:30 p.m. in Light Hall, Room 208. Read More

New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells. Read More

For patients in pediatric intensive care who are at high risk for acute kidney injury (AKI), giving clinicians automated decision support during the electronic order entry process increased the rate of blood testing for AKI by 9%. Read More

New research findings provide insight into the detrimental events that develop in response to H. pylori infection. Read More

A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues. Read More

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease. Read More

An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice. Read More

An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk. Read More