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Department of Medicine Archives

Researchers find novel mechanism of resistance to anti-cancer drugs

Oct. 17, 2017—Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

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New tools to combat kidney fibrosis

Oct. 13, 2017—Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies.

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Researcher targets peanut allergies with Cohen Fund support

Oct. 12, 2017—Scott Smith, M.D., Ph.D., assistant professor of Medicine, has received a 2017 research award from the Stanley Cohen Innovation Fund to test a new therapeutic strategy for peanut allergies. Smith's research could fundamentally change allergy treatment.

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VIGH receives federal grants to fight kidney disease

Oct. 12, 2017—Researchers in the Vanderbilt Institute for Global Health (VIGH) have received two new grants from the National Institutes of Health (NIH) aimed at reducing the risk of kidney disease in HIV-infected adults and improving the treatment of epilepsy in children in Nigeria.

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Chren named inaugural chair of Department of Dermatology

Sep. 29, 2017—As Vanderbilt University Medical Center’s (VUMC) Division of Dermatology transitions from a division within the Department of Medicine to become the Medical Center’s newest clinical department, Mary-Margaret “Meg” Chren, M.D., professor of Dermatology at the University of California, San Francisco (UCSF), has been named to serve as the department’s inaugural chair. She will join the faculty in January 2018.

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Special symposium to honor Moses’ cancer research contributions is Oct. 11

Sep. 21, 2017—A research symposium honoring the career of Harold (Hal) Moses, M.D., who founded and served as director emeritus of Vanderbilt-Ingram Cancer Center, has been slated for Wednesday, Oct. 11, 7:45 a.m. – 3:30 p.m., at the Vanderbilt Student Life Center.

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Grant supports Oates’ research on acetaminophen and stroke

Sep. 21, 2017—John Oates, M.D., a pioneering clinical pharmacologist at Vanderbilt University Medical Center (VUMC), has been awarded a one-year, $20,000 grant from the Brain Aneurysm Foundation to support studies of the stroke-reducing potential of acetaminophen.

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University of Kansas honors Lindsley’s pharmacology research

Sep. 21, 2017—Craig Lindsley, Ph.D., co-director of the Vanderbilt Center for Neuroscience Drug Discovery, has been honored by the University of Kansas with the 2018 Edward E. Smissman Lectureship for his outstanding contributions to the fields of medicinal chemistry and molecular pharmacology.

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Inhibiting obesity

Sep. 15, 2017—An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain.

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Pancreatic cancer development

Aug. 31, 2017—Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease.

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Oxidative stress on the brain

Aug. 23, 2017—Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders.

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Fatty acids and adenoma risk

Aug. 21, 2017—Vanderbilt researchers have found that red blood cell membrane fatty acid content is associated with risk of having colorectal adenomas, with omega-6 fatty acids increasing and omega-3 fatty acids decreasing risk.

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