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Department of Medicine

How salt increases blood pressure

Sep. 5, 2019—Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.

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Cancer susceptibility genes

Aug. 26, 2019—Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations.

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Host-microbe interactions in the gut

Aug. 13, 2019—Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.

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New window on fibrosis

Aug. 8, 2019—A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases.

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Grant bolsters research on myelodysplastic syndromes

Aug. 1, 2019—Michael Savona, MD, has received a competitive grant to develop therapies for patients with myelodysplastic syndromes.

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Study ‘ignites’ link between genes and drug response

Jul. 25, 2019—A national study is seeking to determine whether genetic testing can help physicians choose the best drugs for their patients to relieve pain and depression.

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Sex differences in kidney injury

Jul. 25, 2019—Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.

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Encephalitis identified as rare toxicity of immunotherapy treatment

Jul. 22, 2019—Researchers are chronicling rare but serious toxicities that may occur with immune checkpoint inhibitors, the most widely prescribed class of immunotherapies.

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Madhur receives Presidential Early Career Award

Jul. 18, 2019—Meena Madhur, MD, PhD, has received a Presidential Early Career Award for Scientists and Engineers.

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New look at atherosclerosis

Jul. 11, 2019—A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.

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Biomarkers of DNA methylation can be a predictor of breast cancer risk

Jun. 26, 2019—Biomarkers of DNA methylation, which regulate gene expression, can be a predictor of breast cancer risk.

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Fish oil and cancer prevention

Jun. 24, 2019—Fish oil supplementation provides a modest but beneficial effect on reducing molecules associated with colorectal cancer development.

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