Department Of Medicine

A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection. Read More

Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease. Read More

Laura Dugan strives to bring breakthroughs in neuroscience research and the aging brain together. Read More

Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies. Read More

Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies. Read More

A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1. Read More

Two proteins interact to maintain selenium levels in the brain, and protect neurons from degeneration. Read More

Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered. Read More

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered. Read More

Vanderbilt researchers have found that selenium deficiency may contribute to the racial disparity in lung cancer incidence. Read More

Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders. Read More

A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process. Read More

A particular anti-arrhythmia drug provides a targeted treatment for certain forms of atrial fibrillation. Read More

A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication. Read More

Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation. Read More

Laura Dugan, M.D., the Larry L. Hillblom Chair in Geriatric Medicine at the University of California San Diego (UCSD), will join the Vanderbilt faculty on April 7 to direct Vanderbilt University’s Division of Geriatric Medicine, a division of the Department of Medicine. Read More

A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found. Read More

Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge. Read More

Yale University’s Richard Lifton, M.D., Ph.D., winner of a $3 million, 2014 Breakthrough Prize in Life Sciences for discovering genes and biochemical mechanisms that cause hypertension, will deliver the next Flexner Discovery Lecture March 6. Read More

A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia. Read More