Department Of Medicine

An enzyme that produces bioactive fatty acids has elevated activity in patients with rheumatoid arthritis, supporting further studies to understand its biologic roles in the disease. Read More

Collaboration between a mechanical engineer at Vanderbilt University and a pulmonologist at Vanderbilt University Medical Center (VUMC) has resulted in a National Institutes of Health (NIH) R01 grant that will be used to develop a steerable robotic needle to safely biopsy hard-to-reach lung nodules. Read More

Dan Roden, M.D., Senior Vice President for Personalized Medicine at Vanderbilt University Medical Center (VUMC), was named to receive the 2017 Medicine Alumni Global Lifetime Achievement Award by the Faculty of Medicine of his alma mater, McGill University. Read More

Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered. Read More

Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance. Read More

Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies. Read More

Scott Smith, M.D., Ph.D., assistant professor of Medicine, has received a 2017 research award from the Stanley Cohen Innovation Fund to test a new therapeutic strategy for peanut allergies. Smith's research could fundamentally change allergy treatment. Read More

Researchers in the Vanderbilt Institute for Global Health (VIGH) have received two new grants from the National Institutes of Health (NIH) aimed at reducing the risk of kidney disease in HIV-infected adults and improving the treatment of epilepsy in children in Nigeria. Read More

As Vanderbilt University Medical Center’s (VUMC) Division of Dermatology transitions from a division within the Department of Medicine to become the Medical Center’s newest clinical department, Mary-Margaret “Meg” Chren, M.D., professor of Dermatology at the University of California, San Francisco (UCSF), has been named to serve as the department’s inaugural chair. She will join the faculty in January 2018. Read More

John Oates, M.D., a pioneering clinical pharmacologist at Vanderbilt University Medical Center (VUMC), has been awarded a one-year, $20,000 grant from the Brain Aneurysm Foundation to support studies of the stroke-reducing potential of acetaminophen. Read More

Craig Lindsley, Ph.D., co-director of the Vanderbilt Center for Neuroscience Drug Discovery, has been honored by the University of Kansas with the 2018 Edward E. Smissman Lectureship for his outstanding contributions to the fields of medicinal chemistry and molecular pharmacology. Read More

An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain. Read More

Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease. Read More

Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders. Read More

Vanderbilt researchers have found that red blood cell membrane fatty acid content is associated with risk of having colorectal adenomas, with omega-6 fatty acids increasing and omega-3 fatty acids decreasing risk. Read More

A group of nationally recognized medical information and data management experts has recommended the development of new knowledge software applications that work alongside electronic health record systems (EHRs) to help practicing oncologists access and use the latest genomic information to assist in the treatment of cancer patients. Read More

Based on findings from Vanderbilt investigators and others, clinical trials of estrogen inhibition for pulmonary arterial hypertension have recently been approved and funded by the National Institutes of Health. Read More

New findings could explain the link between chronic stress and reduced survival in women diagnosed with breast cancer, and could lead to new strategies to improve treatment outcomes. Read More

Sara Van Driest, M.D., Ph.D., who is developing methods for precision dosing of pediatric medications at Vanderbilt University Medical Center (VUMC), has received a 2017 Clinical Scientist Development Award from the Doris Duke Charitable Foundation. Read More

Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets. Read More