David Merryman
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Merryman, Lindsley make headway in drug development to cure pulmonary arterial hypertension
Research led by David Merryman, a professor of biomedical engineering, pharmacology and medicine who holds the Walters Family Chair, has resulted in the development of VU6047534, a new drug that treats pulmonary arterial hypertension—a type of high blood pressure that affects arteries in the lungs and in the heart—without serious neurological side effects. Merryman conducted... Read MoreSep 13, 2023
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Vanderbilt scientists make headway in drug development to cure pulmonary arterial hypertension
Biomedical engineer David Merryman and Warren Center for Neuroscience Drug Discovery director Craig Lindsley have developed a new drug that treats PAH, a type of high blood pressure that affects arteries in the lungs and in the heart, without serious neurological side effects. Read MoreSep 13, 2023
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Antibody “road block” enables fine-tuning for cardiac recovery, decreases risk of heart failure
A new study published by Vanderbilt mechanobiology researchers details a possible solution for fine-tuning inflammation and cellular activity in cardiac recovery – thanks to an antibody initially developed for rheumatoid arthritis. Read MoreSep 19, 2019
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Study links Celebrex, heart valve calcification after earlier research declared drug safe
A big-data analysis of patient records at Vanderbilt University has found a link specifically between Celebrex and heart valve calcification. Read MoreFeb 22, 2019
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Vanderbilt study suggests way to prevent rare lung disease
Pulmonary hypertension may be treated by targeting a bone marrow cell that normally promotes the growth of new blood vessels, according to new research by David Merryman. Read MoreNov 15, 2018
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Drug developed for arthritis could be first to stop heart valve calcification
The first drug to treat calcification of heart valves may be one originally designed for rheumatoid arthritis. Read MoreJun 12, 2017
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Organ-on-a-chip mimics heart’s biomechanical properties
Scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart’s amazing biomechanical properties in order to study cardiac disease, develop heart drugs. Read MoreFeb 22, 2017
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Hypertension hiatus
New findings offer a potential strategy for preventing heritable pulmonary arterial hypertension. Read MoreFeb 23, 2016
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Baby hearts need rhythm to develop correctly
The mechanical forces generated by the rhythmic expansion and contraction of cardiac muscle cells play an active role in the initial stage of heart valve formation. Read MoreFeb 18, 2014
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Cell connections key in valve disease
A protein that connects cells together participates in the calcification that occurs in heart valve disease. Read MoreFeb 14, 2013
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VUCast: Eat More, Lose Weight!
This Week on VUCast, Vanderbilt’s online newscast: Eat more, lose weight! A Vandy nutritionist shows how it works Anger in the court! Why ticked-off judges may be better judges. See what inspires some of our professors to teach. Read MoreJan 16, 2013
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Preventing hardened heart valves
Blocking a serotonin receptor may provide a novel therapy for heart valve disease. Read MoreDec 26, 2012
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Heart for Research: Energized by the pursuit, David Merryman and his team look for answers to cardiovascular disease
Talk to people who know David Merryman best, and one adjective is heard frequently: passionate. Talk to Merryman yourself and it is easy to see why. Discussing his research, the assistant professor of biomedical engineering seems ready to leap out of his chair at any moment, perhaps to tweak the… Read MoreNov 3, 2011
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