Charles Sanders

Medicine often takes a one-size-fits-all approach, but a disorder’s root cause can vary. Vanderbilt researchers have found that, for people with long QT syndrome, a heart condition that causes an irregular heartbeat, a more tailored approach could be beneficial. The research, led by Vanderbilt University Professor of Biochemistry and Vice Dean of Basic Sciences Charles Sanders and Northwestern University Professor and Chair of Pharmacology Dr. Al George, was published in PNAS in February 2025. Read More

The CMT Research Foundation, a non-profit focused solely on delivering treatments and cures for Charcot-Marie-Tooth disease*, has invested in a project at Vanderbilt University School of Medicine Basic Sciences that seeks to treat the problem of overproduction of PMP22, the primary genetic cause of CMT in patients with CMT1A. Read More

Charles Sanders, PhD, and colleagues show how a “supertrafficking” mutant potassium channel contributes to heart rhythm abnormalities. Read More

Recent advances in imaging technology are enabling Vanderbilt scientists to gain unprecedented views of how molecules, cells and tissues work together, yielding radical new insights into the causes, treatment and prevention of disease. Read More

Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders. Read More

Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear. Read More

A new protein structure may guide the development of Alzheimer's therapeutics. Read More

Charles Sanders, Ph.D., has been named associate dean for Research in the Basic Sciences of Vanderbilt University School of Medicine. Read More

Integrins are membrane proteins made up of combinations of different “alpha” and “beta” subunits that enable cells throughout the body to interact with their surroundings. Read More

A research team led by structural biologists from Vanderbilt University has come up with the first detailed molecular explanation for a factor that may contribute to the so-called cystic fibrosis (CF) “gender gap.” Read More

Pioneering Vanderbilt University structural biologist Charles Sanders, Ph.D., has been named interim editor of Biochemistry, an eminent journal for publishing research articles about the molecular structure, mechanisms and interactions of important biological molecules. Read More

(photo by Joe Howell) Catherine Deatherage, a graduate student in the lab of Charles Sanders, Ph.D., received this year’s Leon W. Cunningham Award for Excellence in Biochemistry during a presentation last week. The award, named for the late Leon Cunningham, Ph.D., former chair of the Department of Biochemistry,… Read More

Chelsea Sullivan, a graduate student in the lab of Bruce Carter, Ph.D., received this year’s Leon W. Cunningham Award for Excellence in Biochemistry during a presentation last week. The award, named for the late Leon Cunningham, Ph.D., former chair of the Department of Biochemistry, is given annually… Read More

Charles Sanders, Ph.D., professor of Biochemistry, has been selected as a recipient of the 2013 Hans Neurath Award from the Protein Society. He shares the honor with Jennifer Doudna, Ph.D., a Howard Hughes Medical Institute investigator at the University of California, Berkeley. Read More

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development. Read More

Several Vanderbilt researchers have collaborated with this year's Nobel Chemistry winners. Read More

The molecular structure of a protein involved in Alzheimer’s disease – and the surprising discovery that it binds cholesterol – could lead to new therapeutics for the memory-robbing disease. Read More

Vanderbilt University’s acquisition of a 900 megahertz nuclear magnetic resonance (NMR) spectrometer will accelerate studies on cancer and Alzheimer’s disease. Read More