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cell and developmental biology Archives

New therapeutic target for diabetes

Aug. 20, 2015—The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes.

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Macara lands award to explore cancer cell behavior

Aug. 13, 2015—Vanderbilt’s Ian Macara, Ph.D., has won an Outstanding Investigator Award from the National Cancer Institute (NCI) — nearly $6.6 million over seven years — to support the “unusual potential” of his research, which seeks to understand and predict cancer cell “behavior.”

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Worldwide Cancer Research lauds Macara’s contributions

Jul. 30, 2015—Ian Macara, Ph.D., professor and chair of the Department of Cell and Developmental Biology, recently returned from Scotland, where he received this year’s Colin Thomson Memorial Medal for his contributions to cancer research.

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Stem cells, Wnt signaling explored at Discovery lecture

Apr. 30, 2015—Our tissues are in a constant state of flux — cells are lost and cells are generated, with local signals and stem cells maintaining the balance, said Roel Nusse, Ph.D., during last week’s Flexner Discovery Lecture.

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VU team explores new cholesterol processing pathway

Apr. 23, 2015—A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing.

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Boosting beta cells in diabetes

Apr. 20, 2015—New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.

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Surprising finding in the kidney

Apr. 16, 2015—TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling.

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Tissue regulation expert Nusse set for next Discovery Lecture

Apr. 16, 2015—Roel Nusse, Ph.D., an expert in the regulation of tissue growth and development by Wnt signaling pathways, will deliver the next Flexner Discovery Lecture on Thursday, April 23.

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Cancer signaling pathway blocker

Apr. 3, 2015—Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer.

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Aging insights from budding yeast

Apr. 2, 2015—The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.

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‘Docking stations’ on chromosomes new anti-cancer target

Mar. 26, 2015—Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks.

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Zanic’s journey to the lab followed winding path

Mar. 5, 2015—It’s roughly 5,000 miles from Croatia to Tennessee as the crow flies.

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