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cell and developmental biology Archives

Tissue regulation expert Nusse set for next Discovery Lecture

Apr. 16, 2015—Roel Nusse, Ph.D., an expert in the regulation of tissue growth and development by Wnt signaling pathways, will deliver the next Flexner Discovery Lecture on Thursday, April 23.

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Cancer signaling pathway blocker

Apr. 3, 2015—Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer.

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Aging insights from budding yeast

Apr. 2, 2015—The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.

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‘Docking stations’ on chromosomes new anti-cancer target

Mar. 26, 2015—Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks.

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Zanic’s journey to the lab followed winding path

Mar. 5, 2015—It’s roughly 5,000 miles from Croatia to Tennessee as the crow flies.

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Gene profile predicts metastasis

Feb. 9, 2015—A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.

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New clue to a devastating disease

Jan. 28, 2015—New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

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Twelve Vanderbilt faculty elected AAAS fellows

Nov. 24, 2014—Twelve members of Vanderbilt's faculty have been elected fellows of the American Association for the Advancement of Science for their “scientifically or socially distinguished efforts to advance science or its applications.”

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VU study reveals factor’s new role in cell division, migration

Oct. 30, 2014—Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.

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Antibiotics, fetal vessel defect linked

Oct. 15, 2014—Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis.

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Long-range signaling to stem cells

Oct. 9, 2014—The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis.

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Study finds coronary arteries hold heart-regenerating cells

Aug. 20, 2014—Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered.

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