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cell and developmental biology Archives

Gene profile predicts metastasis

Feb. 9, 2015—A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.

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New clue to a devastating disease

Jan. 28, 2015—New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

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Twelve Vanderbilt faculty elected AAAS fellows

Nov. 24, 2014—Twelve members of Vanderbilt's faculty have been elected fellows of the American Association for the Advancement of Science for their “scientifically or socially distinguished efforts to advance science or its applications.”

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VU study reveals factor’s new role in cell division, migration

Oct. 30, 2014—Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.

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Antibiotics, fetal vessel defect linked

Oct. 15, 2014—Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis.

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Long-range signaling to stem cells

Oct. 9, 2014—The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis.

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Study finds coronary arteries hold heart-regenerating cells

Aug. 20, 2014—Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered.

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Pioneers of Discovery: Investigator taps into artistic side to reveal cells’ secrets

May. 29, 2014—Dylan Burnette, Ph.D., points to one of the many striking photographs on his office walls. It’s a picture of a cell — a microscopic image showing yellow squiggles, bright purple lines and a turquoise oval on a black background, and it looks like abstract art.

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Potential mechanism for myeloma drug’s variable toxicity

Apr. 30, 2014—A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication.

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Prominent scientist, respected administrator Susan Wente named Vanderbilt provost and vice chancellor for academic affairs

Apr. 28, 2014—After an extensive national search, Susan R. Wente has been named provost and vice chancellor for academic affairs, Chancellor Nicholas S. Zeppos announced today.

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Nutrient-absorbing surface’s assembly revealed: study

Apr. 17, 2014—Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.

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Development and disease in the aorta

Apr. 2, 2014—Smooth muscle cells that line the aorta differ in development but not in the adult, a finding that has implications for understanding aortic development and disease.

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