Cell And Developmental Biology
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Bad “traffic” linked to cancer
Understanding how signaling molecules are transported within and out of the cell may help to uncover the causes of certain cancers. Read MoreSep 3, 2015
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New Vanderbilt Eye Institute member to lecture Aug. 31
Sabine Fuhrmann kicks off the CDB Monday Seminar Series on Aug. 31. Read MoreAug 21, 2015
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New therapeutic target for diabetes
The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes. Read MoreAug 20, 2015
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Macara lands award to explore cancer cell behavior
Vanderbilt’s Ian Macara, Ph.D., has won an Outstanding Investigator Award from the National Cancer Institute (NCI) — nearly $6.6 million over seven years — to support the “unusual potential” of his research, which seeks to understand and predict cancer cell “behavior.” Read MoreAug 13, 2015
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Worldwide Cancer Research lauds Macara’s contributions
Ian Macara, Ph.D., professor and chair of the Department of Cell and Developmental Biology, recently returned from Scotland, where he received this year’s Colin Thomson Memorial Medal for his contributions to cancer research. Read MoreJul 30, 2015
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Stem cells, Wnt signaling explored at Discovery lecture
Our tissues are in a constant state of flux — cells are lost and cells are generated, with local signals and stem cells maintaining the balance, said Roel Nusse, Ph.D., during last week’s Flexner Discovery Lecture. Read MoreApr 30, 2015
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VU team explores new cholesterol processing pathway
A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing. Read MoreApr 23, 2015
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Boosting beta cells in diabetes
New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas. Read MoreApr 20, 2015
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Surprising finding in the kidney
TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling. Read MoreApr 16, 2015
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Tissue regulation expert Nusse set for next Discovery Lecture
Roel Nusse, Ph.D., an expert in the regulation of tissue growth and development by Wnt signaling pathways, will deliver the next Flexner Discovery Lecture on Thursday, April 23. Read MoreApr 16, 2015
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Cancer signaling pathway blocker
Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer. Read MoreApr 3, 2015
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Aging insights from budding yeast
The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered. Read MoreApr 2, 2015
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‘Docking stations’ on chromosomes new anti-cancer target
Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks. Read MoreMar 26, 2015
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Zanic’s journey to the lab followed winding path
It’s roughly 5,000 miles from Croatia to Tennessee as the crow flies. Read MoreMar 5, 2015
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Gene profile predicts metastasis
A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found. Read MoreFeb 9, 2015
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New clue to a devastating disease
New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease. Read MoreJan 28, 2015
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Twelve Vanderbilt faculty elected AAAS fellows
Twelve members of Vanderbilt's faculty have been elected fellows of the American Association for the Advancement of Science for their “scientifically or socially distinguished efforts to advance science or its applications.” Read MoreNov 24, 2014
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VU study reveals factor’s new role in cell division, migration
Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery. Read MoreOct 30, 2014
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Antibiotics, fetal vessel defect linked
Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis. Read MoreOct 15, 2014
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Long-range signaling to stem cells
The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis. Read MoreOct 9, 2014