cell and developmental biology
Stem cells, Wnt signaling explored at Discovery lecture
Apr. 30, 2015—Our tissues are in a constant state of flux — cells are lost and cells are generated, with local signals and stem cells maintaining the balance, said Roel Nusse, Ph.D., during last week’s Flexner Discovery Lecture.
VU team explores new cholesterol processing pathway
Apr. 23, 2015—A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing.
Boosting beta cells in diabetes
Apr. 20, 2015—New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.
Surprising finding in the kidney
Apr. 16, 2015—TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling.
Tissue regulation expert Nusse set for next Discovery Lecture
Apr. 16, 2015—Roel Nusse, Ph.D., an expert in the regulation of tissue growth and development by Wnt signaling pathways, will deliver the next Flexner Discovery Lecture on Thursday, April 23.
Cancer signaling pathway blocker
Apr. 3, 2015—Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer.
Aging insights from budding yeast
Apr. 2, 2015—The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.
‘Docking stations’ on chromosomes new anti-cancer target
Mar. 26, 2015—Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks.
Zanic’s journey to the lab followed winding path
Mar. 5, 2015—It’s roughly 5,000 miles from Croatia to Tennessee as the crow flies.
Gene profile predicts metastasis
Feb. 9, 2015—A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.
New clue to a devastating disease
Jan. 28, 2015—New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.
Twelve Vanderbilt faculty elected AAAS fellows
Nov. 24, 2014—Twelve members of Vanderbilt's faculty have been elected fellows of the American Association for the Advancement of Science for their “scientifically or socially distinguished efforts to advance science or its applications.”