Cancer Biology

An experimental melanoma drug may be beneficial for patients not eligible for targeted therapies. Read More

Measuring levels of an enzyme in head and neck tumors may indicate how the tumor will respond to radiation therapy. Read More

Cellular pathways altered by chronic exposure to cigarette smoke may reveal new biomarkers to assess smoking-induced lung cancer risk. Read More

New information about signaling pathways involved in colorectal cancer could aid in assessing prognosis and identifying new therapeutic targets for the disease. Read More

Investigators at Vanderbilt-Ingram Cancer Center and several other centers may be one step closer to finding out why some melanoma patients relapse after treatment with a promising new drug. Read More

A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer. Read More

Host cell protein may be a target for strategies to limit spread of virus-induced squamous cell cancers. Read More

Molecular players involved in colon cancer progression could provide new biomarkers to indicate invasiveness and prognosis. Read More

Loss of the protein p120 in the intestinal lining sets the stage for tumor formation. Read More

Blocking a certain protein during radiation to treat brain cancers could protect the brain’s thinking powers. Read More

A gene signature may be useful in predicting outcomes for patients with rhabdomysarcoma, a form of cancer most commonly diagnosed in children. Read More

David Gius, M.D., Ph.D., and colleagues are studying an aging-associated protein’s role in the development of breast cancer in older women. (Vanderbilt University/photo by Mary Donaldson) The most common type of breast cancer in older women – estrogen and progesterone receptor (ER/PR) positive breast cancer – has been linked to… Read More