Aliquots
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Limiting breast cancer metastasis
Vanderbilt researchers have identified a new target for blocking breast cancer metastasis. Read MoreAug 28, 2014
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Enzyme holds the door for influenza
Compounds developed at Vanderbilt University may offer a new way to block influenza infection. Read MoreAug 20, 2014
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Keeping an eye on blast trauma
Understanding the cellular and molecular responses of the eye to blast injury could guide new treatment development. Read MoreAug 19, 2014
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Weight regain after gastric bypass
Early weight regain after gastric bypass surgery does not reverse metabolic improvements, and the "hunger hormone" ghrelin might indicate who is susceptible to weight regain. Read MoreAug 15, 2014
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Growth factor blockade targets breast tumors
Inhibition of BMP growth factor signaling reduces breast tumor burden and metastasis. Read MoreAug 14, 2014
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Low selenium and lung cancer
Vanderbilt researchers have found that selenium deficiency may contribute to the racial disparity in lung cancer incidence. Read MoreAug 6, 2014
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Drug discovery clues in network map
Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies. Read MoreAug 5, 2014
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Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels
Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders. Read MoreAug 1, 2014
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New target for breast cancer therapy
The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics. Read MoreJul 31, 2014
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Treatments for frog fungus
The fungicide amphotericin B may be a useful treatment for a frog fungus that is killing amphibians worldwide. Read MoreJul 25, 2014
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Natural killer cells don’t clear HMPV
Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments. Read MoreJul 23, 2014
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Reversing stress-induced anxiety
Augmenting the signals of natural “endocannabinoids” in the brain may be a promising approach for treating mood and anxiety disorders. Read MoreJul 21, 2014
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Neural receptor for reovirus
A newly identified receptor allows mammalian reovirus to infect neurons, shedding light on factors important for viral encephalitis. Read MoreJul 18, 2014
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Regulating immune regulators
Understanding how to control the generation of regulatory T cells could have important implications for treating autoimmunity and cancer. Read MoreJul 17, 2014
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Factor impacts bone toughness
The factor ATF4 has a role in the toughness of bone and its resistance to fracture, suggesting new therapeutic targets. Read MoreJun 16, 2014
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How ABC transporters move molecules
New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis. Read MoreJun 13, 2014
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Exploring Wilms tumor race disparity
Unique molecular "fingerprints" could explain the disparity in Wilms tumor incidence and point to novel, race-specific therapeutic targets. Read MoreMay 29, 2014
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Respiratory virus vaccine candidate
Virus-like particles containing a protein from human metapneumovirus are a promising vaccine candidate for this respiratory virus. Read MoreMay 27, 2014
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Repair protein’s DNA recognition motif
Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer. Read MoreMay 23, 2014
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Cellular forces aid tumor invasion
The contractile machinery inside tumor cells increases invasive properties, suggesting it might be a good target to inhibit cancer cell spread. Read MoreMay 22, 2014