Aliquots

Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease. Read More

The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility. Read More

A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures. Read More

Using patients’ health records to assess preparedness for hospital discharge is more effective at predicting readmission or death than commonly used questionnaires. Read More

A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease. Read More

A new compound developed at Vanderbilt treats multiple symptoms of schizophrenia in an animal model, without causing sedation. Read More

The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies. Read More

A new animal model can be used to “dissect” the inflammatory response to infection. Read More

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish. Read More

Actin and microtubule cytoskeletons are coordinated during cytokinesis – the process that separates one cell into two and is linked to events underlying cancer. Read More

Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read More

Vanderbilt researchers have defined a mechanism that limits liver cell proliferation after injury in order to preserve critical metabolic functions. Read More

New findings offer a potential strategy for preventing heritable pulmonary arterial hypertension. Read More

An inability to recognize faces may be an important mechanism underlying social inhibition and may contribute to, or maintain, social anxiety. Read More

Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients. Read More

Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients. Read More

Vanderbilt researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding. Read More

Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease. Read More

Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance. Read More

The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring. Read More