Aliquots
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ROCKs and cancer invasion
The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies. Read MoreMar 17, 2016
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Eye of a cytokine storm
A new animal model can be used to “dissect” the inflammatory response to infection. Read MoreMar 9, 2016
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Fat hormone’s role in zebrafish
The hormone leptin regulates glucose balance, but not fat stores, in zebrafish. Read MoreMar 8, 2016
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A clue to cell cleavage
Actin and microtubule cytoskeletons are coordinated during cytokinesis – the process that separates one cell into two and is linked to events underlying cancer. Read MoreMar 7, 2016
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Melanoma response to immune therapy
Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read MoreMar 3, 2016
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Liver balancing act
Vanderbilt researchers have defined a mechanism that limits liver cell proliferation after injury in order to preserve critical metabolic functions. Read MoreFeb 24, 2016
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Hypertension hiatus
New findings offer a potential strategy for preventing heritable pulmonary arterial hypertension. Read MoreFeb 23, 2016
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Face recognition and social anxiety
An inability to recognize faces may be an important mechanism underlying social inhibition and may contribute to, or maintain, social anxiety. Read MoreFeb 19, 2016
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Combining treatments for melanoma
Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients. Read MoreFeb 18, 2016
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Overcoming lung cancer drug resistance
Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients. Read MoreFeb 10, 2016
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Therapies to prevent preterm birth
Vanderbilt researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding. Read MoreFeb 9, 2016
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Building intestinal brush borders
Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease. Read MoreFeb 8, 2016
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Dynamics of a drug resistance transporter
Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance. Read MoreFeb 5, 2016
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Wound-healing scaffolds
The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring. Read MoreJan 27, 2016
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Using MRI to assess myelin health
Vanderbilt investigators report an improved model for estimating brain health, using MRI. Read MoreJan 25, 2016
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Faulty building blocks in DNA
An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations. Read MoreJan 22, 2016
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New targets for diabetic retinopathy
Certain protein factors have been identified as attractive targets for treating diabetic retinopathy, a major cause of blindness in adults. Read MoreJan 21, 2016
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Platelet protein modification
Vanderbilt investigators have identified a new biomarker to assess platelet function. Read MoreJan 13, 2016
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Improving colonoscopy prep
Providing an educational booklet on colonoscopy preparation increased the odds of an adequate quality of bowel preparation by more than two-fold. Read MoreJan 11, 2016
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Copying chromosome caps
Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports. Read MoreJan 8, 2016