Aliquots

Two factors commonly used to evaluate patients with sickle cell disease are associated with each other and can predict increased mortality, Vanderbilt researchers have discovered. Read More

Although nitrous oxide was less effective than epidural anesthesia for pain management during labor, mothers who used nitrous oxide were equally satisfied with their childbirth experience. Read More

A signaling protein overexpressed in upper gastrointestinal cancers is an attractive therapeutic target. Read More

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection. Read More

Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions. Read More

Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance. Read More

An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered. Read More

High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells. Read More

“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity. Read More

The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response. Read More

Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways. Read More

Cognitive and attention deficits observed in children following surgery before age 5 to repair congenital heart defects likely will persist into their teens and young adulthood. Read More

To improve medical management of crisis situations, clinicians should be trained to use cognitive aids – checklists and concise manuals. Read More

Vanderbilt investigators recommend that the presence of tumor deposits in the abdomen be included when staging midgut neuroendocrine tumors. Read More

A new computer algorithm developed at Vanderbilt could save billions of dollars in health care costs by identifying patients at risk for readmission after being hospitalized for heart failure. Read More

A new method will make it possible to study solid tumors and healthy tissues using mass cytometry. Read More

Vanderbilt investigators have discovered how a promising cancer immunotherapy causes brain swelling, findings that could lead to ways to protect brain function while fighting cancers. Read More

A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells. Read More

Vanderbilt investigators have discovered how antidepressant medicines that block serotonin uptake can increase bleeding risk. Read More

Vanderbilt researchers have discovered steps in the regulation of a key enzyme that builds the basement membrane, a structure that undergirds nearly all animal tissues. Read More