Aliquots
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A lipid’s role in cell division
Lipids in the plasma membrane regulate the position of the contractile ring that is required for cell division, Vanderbilt researchers have discovered. Read MoreNov 10, 2017
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HIV outreach and return to care
When chronic disease patients let their care lapse and fail to show for clinic appointments, it may behoove clinics to reach out and encourage a return to care. Read MoreNov 9, 2017
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Bioactive lipids and rheumatoid arthritis
An enzyme that produces bioactive fatty acids has elevated activity in patients with rheumatoid arthritis, supporting further studies to understand its biologic roles in the disease. Read MoreNov 1, 2017
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Disparities in influenza outcomes
Neighborhood determinants – represented by census tract data – contribute to the risk of influenza hospitalization and could be used to guide interventions such as vaccinations to high-risk areas. Read MoreOct 30, 2017
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Impulsivity in Parkinson’s Disease
A noninvasive MRI technique may help predict a troubling side effect of common medications for Parkinson’s Disease and improve clinical treatment plans. Read MoreOct 27, 2017
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Calcium intake and colorectal cancer
Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered. Read MoreOct 18, 2017
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Gender, pain and dementia
Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease. Read MoreOct 16, 2017
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New tools to combat kidney fibrosis
Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies. Read MoreOct 13, 2017
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A switch for autoimmunity
Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies. Read MoreOct 12, 2017
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Boosting sarcoma cell death
A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas. Read MoreOct 4, 2017
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Delirium, benzos and the pediatric ICU
With other risk factors held equal, children who received a benzodiazepine sedative drug were nearly three times more likely to experience delirium – confused thought – the following day. Read MoreOct 2, 2017
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Novel insights to antibiotic targets
New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines. Read MoreSep 29, 2017
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Cellular calcium handling in diabetes
Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health. Read MoreSep 28, 2017
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NSAIDs, genetics and miscarriage
A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage. Read MoreSep 20, 2017
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Medication safety in the ICU
Facilitated reporting of medication-related events in the intensive care unit can provide opportunities for optimizing quality of care and patient safety. Read MoreSep 19, 2017
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Inhibiting obesity
An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain. Read MoreSep 15, 2017
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Acid reflux cancer link
Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer. Read MoreSep 14, 2017
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Heat a trigger for seizures
Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation. Read MoreSep 6, 2017
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Pain and Alzheimer’s disease
Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked. Read MoreSep 5, 2017
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Restricting HIV-1 infection
Vanderbilt researchers are discovering ways that host proteins block HIV-1 infection, which could suggest new avenues for treatment. Read MoreSep 1, 2017