Aliquots

Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease. Read More

Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies. Read More

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies. Read More

A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas. Read More

With other risk factors held equal, children who received a benzodiazepine sedative drug were nearly three times more likely to experience delirium – confused thought – the following day. Read More

New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines. Read More

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health. Read More

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage. Read More

Facilitated reporting of medication-related events in the intensive care unit can provide opportunities for optimizing quality of care and patient safety. Read More

An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain. Read More

Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer. Read More

Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation. Read More

Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked. Read More

Vanderbilt researchers are discovering ways that host proteins block HIV-1 infection, which could suggest new avenues for treatment. Read More

Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease. Read More

Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders. Read More

Vanderbilt researchers have found that red blood cell membrane fatty acid content is associated with risk of having colorectal adenomas, with omega-6 fatty acids increasing and omega-3 fatty acids decreasing risk. Read More

Assessing brain functional and structural connectivity in patients with temporal lobe epilepsy may be a useful way to identify the best candidates for surgical treatment. Read More

Based on findings from Vanderbilt investigators and others, clinical trials of estrogen inhibition for pulmonary arterial hypertension have recently been approved and funded by the National Institutes of Health. Read More

New findings could explain the link between chronic stress and reduced survival in women diagnosed with breast cancer, and could lead to new strategies to improve treatment outcomes. Read More