Aliquots

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease. Read More

Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC. Read More

A new study published in Neurology reports the drug trofinetide has proven safe and effective in treating core symptoms of Rett syndrome in female children and adolescents. Read More

Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders. Read More

Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read More

The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections. Read More

A drug in use clinically to help make vaccines more effective may be a powerful new tool for fighting antibiotic-resistant infections. Read More

Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis. Read More

Common sequences of antibodies against HIV may be key to developing a successful vaccine strategy for the virus. Read More

Vanderbilt scientists have discovered that a certain enzyme plays a crucial role in preventing obesity-related cardiac dysfunction. Read More

Genomic sequences have revealed that Florida is a major source of a mosquito-borne virus that causes disease in horses and humans. Read More

A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members. Read More

Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry. Read More

Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses. Read More

An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. Read More

Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage. Read More

A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer. Read More

Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function. Read More

A protease gene family may be new targets for treating mitral valve disease, which causes blood to flow backwards in the heart. Read More

The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read More