Health And Medicine

A protein that connects cells together participates in the calcification that occurs in heart valve disease. Read More

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance. Read More

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development. Read More

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart. Read More

The kidney can mediate its own repair through proliferation of resident immune system cells. Read More

Structural studies reveal a new framework for understanding a central player in DNA processing. Read More

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk. Read More

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development. Read More

Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments. Read More

It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc. Read More

AstraZeneca and Vanderbilt University have signed a research collaboration agreement to identify candidate drugs aimed at treating psychosis and other neuropsychiatric symptoms associated with major brain diseases such as Alzheimer’s disease and schizophrenia. Read More

There may be a biological basis for separate doll and dump truck aisles in the toy store. Read More

Clinical pharmacologist Jens Titze, M.D., and colleagues have discovered that – in contrast to the prevailing dogma – human sodium levels fluctuate rhythmically with 7-day and monthly cycles. Read More

Blocking a serotonin receptor may provide a novel therapy for heart valve disease. Read More

Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer. Read More

Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds. Read More

Archived tissue samples are yielding new disease biomarkers. Read More

A new study identifies interactions between genes and nutrients that may participate in determining levels of cholesterol and triglycerides. Read More

A rare genetic syndrome provides new clues to lung scarring (pulmonary fibrosis), a potentially deadly consequence of many lung diseases. Read More

Components of human breast milk help ward off viral infection, a new study shows. Read More