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Health and Medicine

‘Detangler’ binds, bends and cuts DNA

Mar. 2, 2012—New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents.

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Early study hints at ‘brown fat’ as potential diabetes treatment

Mar. 2, 2012—A new study finds long-lasting reversal of diabetes is possible without insulin through transplantation of brown fat tissue.

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‘Toolkit’ makes bedtime less stressful for children with autism

Feb. 27, 2012—A new resource developed by the Vanderbilt Kennedy Center could improve sleep for children with autism.

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Switch to cooling blanket spurs new infant brain research

Feb. 24, 2012—Using a cooling blanket with newborns who have suffered from oxygen deprivation allows researchers to study what is happening in the brain and what brain cooling therapy can achieve.

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Studies pinpoint new anti-cancer drug target

Feb. 23, 2012—Vanderbilt researchers have discovered a new molecular participant in the Wnt signaling pathway, which plays important roles in cell growth, development and cancer.

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New melanoma drug nearly doubles survival in majority of patients

Feb. 23, 2012—Investigators from Vanderbilt-Ingram Cancer Center and 12 other centers in the United States and Australia have found that a new drug for patients with metastatic melanoma nearly doubled median overall survival.

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‘Acid test’ for cervical cancer

Feb. 21, 2012—An inexpensive, low-tech test for cervical cancer may be a good option for screening for the disease among HIV-infected women in developing countries.

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How Cool Cap saved this baby’s life

Feb. 20, 2012—Monroe Carell Jr. Children’s Hospital at Vanderbilt has treated more than 200 babies with Cool Cap since 2006. Researchers are looking at ways to extend the therapy to premature infants.

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Stem cells take heart

Feb. 20, 2012—Signaling pathway discoveries suggest ways to induce stem cells to become cardiac muscle cells, which could be useful for regenerating damaged heart muscle.

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Investigators seek clues to paradox of atrial fibrillation risk

Feb. 17, 2012—Vanderbilt researchers are seeking genetic clues to explain why risk factors for AF are more prevalent in African-Americans but their incidence of the disease is lower than European-Americans.

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Memory intact in early psychosis

Feb. 16, 2012—Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities.

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On the tail of RSV infection mechanism

Feb. 15, 2012—New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly.

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