Research
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Team seeks to shed light on rare immune-mediated adverse drug reaction
Thirty years ago when she was 16, Katie Niemeyer was prescribed carbamazepine for depression. Three weeks later she was in a St. Louis, Missouri, burn unit with second and third degree burns all over her body. “My parents were told the chances of me surviving were slim,” she said. Read MoreMay 31, 2018
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New research finds lung cancer risk drops substantially within five years of quitting smoking
Just because you stopped smoking years ago doesn’t mean you’re out of the woods when it comes to developing lung cancer. That’s the “bad” news. The good news is your risk of lung cancer drops substantially within five years of quitting. Read MoreMay 29, 2018
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Prehistoric people also likely disrupted by environmental change
A prehistoric community in the Mississippi Delta may have abandoned a large ceremonial site after the bayou it sits on began to dry up. Read MoreMay 24, 2018
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New method to thwart false positives in CT-lung cancer screening
A team of investigators led by Fabien Maldonado, MD, associate professor of Medicine at Vanderbilt, and Tobias Peikert, MD, assistant professor of Medicine at Mayo Clinic, Rochester, Minnesota, has identified a new technology to address false positives in CT-based lung cancer screening. The study was published in the latest issue of PLOS One. Read MoreMay 24, 2018
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Evolution of a deadly virus
Genomic sequences have revealed that Florida is a major source of a mosquito-borne virus that causes disease in horses and humans. Read MoreMay 23, 2018
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New target to stop Ebola
A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members. Read MoreMay 21, 2018
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Consumers focus on food types, not portions, when it comes to perceived healthiness
New research from Vanderbilt University finds that consumers lose sight of caloric intake when they think they’re eating healthy foods. Read MoreMay 18, 2018
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Shaping reward circuits
Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry. Read MoreMay 18, 2018
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Alphavirus “Achilles heel”
Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses. Read MoreMay 17, 2018
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Insect gene allows reproductive organs to cope with harmful bacteria
Bordenstein’s team studied Nasonia parasitic wasps, which are about the size of a sesame seed, and they serve as one of the best models to dissect and characterize the evolution of insect genomes. Read MoreMay 17, 2018
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Study finds sharp rise in suicide risk for children
The number of school-age children and adolescents hospitalized for suicidal thoughts or attempts has more than doubled since 2008, according to a new Vanderbilt-led study published in Pediatrics. Read MoreMay 17, 2018
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Early discharge of NAS infants prolongs treatment
Infants who are diagnosed with drug withdrawal after birth who are treated with medication as outpatients at home are treated three times longer than infants treated solely as inpatients, according to a new Vanderbilt study. Read MoreMay 17, 2018
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Study finds acetaminophen helps reduce acute kidney injury risk in children following cardiac surgery
Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics. Read MoreMay 14, 2018
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Grant bolsters kidney cancer immunotherapy research
W. Kimryn Rathmell, MD, PhD, Cornelius Abernathy Craig Professor of Medicine and director of the Division of Hematology and Oncology at Vanderbilt-Ingram Cancer Center (VICC), has received a grant to research the role of immunosuppression in the tumor microenvironment for kidney cancer. Read MoreMay 10, 2018
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Study finds generic options offer limited savings for expensive drugs
Generic drug options did not reduce prices paid for the cancer therapy imatinib (Gleevec), according to a Health Affairs study released this week. Read MoreMay 9, 2018
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Putting the brakes on sepsis
An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. Read MoreMay 9, 2018
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Getting robotic surgical tools from the lab to the operating room
Nabil Simaan’s Advanced Robotics and Mechanism Applications Laboratory at Vanderbilt leads the way in advancing several robotics technologies for medical use, including miniature robots for single small-incision, cochlear implant and minimally invasive throat surgeries. Read MoreMay 8, 2018
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Records point to drug-drug interaction
Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage. Read MoreMay 7, 2018
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New breast cancer targets
A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer. Read MoreMay 4, 2018
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Understanding HDL structure
Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function. Read MoreMay 3, 2018