Research

Ointments like Neosporin contain the antibiotic neomycin, which works great to kill bacteria on the outside of the body when you scrape your knee or have a hangnail. But inside the body, neomycin does more harm than good—kidney and neurological damage and deafness. Research Assistant Professor Bhawik Jain and colleagues in his lab have figured out why that is, and how to stop it. This could make neomycin another tool in the fight against antibiotic-resistant bacteria. Read More

Much of the human brain is still a mystery, largely because it’s pretty difficult to see what’s going on in there. Assistant Professor Daniel Gonzales and the team in his lab are working to make that easier. They’re using experimental platforms that record brain activity with unprecedented precision on all levels. It works on everything from whole-brain networks to individual synapses—tiny gaps between brain cells that are one-tenth the width of a human hair. “We can … really detail pictures of brain activity during learning,” Gonzales said. “And then we can apply that to study diseases that degrade learning.” Read More

Road closures are a pain—and sometimes they’re not even supposed to be happening. A project by senior research scientist Ayan Mukhopadhyay is working to develop a system—SENTRY—that uses AI to help city inspectors find and address unauthorized road closures in Nashville. “The system has the potential to save millions in unpaid permit fees, reduce external inspection costs and minimize disruptions for residents, commuters and local businesses,” Mukhopadhyay said. His research is supported by a $697,000 grant that's part of NSF's CIVIC Innovation Challenge. Read More