Research

RESEARCH SPARK: Learn a key tool new faculty leader Kristina Thomas Dreifuerst is using to prepare the next generation of nurses. Read More

The role of artificial intelligence in drug discovery has been limited by machine learning methods that fail when they encounter chemical structures they weren’t “trained” on. Assistant Professor Benjamin Brown has written a paper suggesting a more targeted approach: using a task-specific model architecture that’s intentionally restricted to learn from a representation of the interaction space between a protein and a drug molecule and be better able to generalize and figure out which compound might best interact with that protein. That’s important, because identifying those compounds early cuts the costs and time involved in developing drugs. Read More

Health inequity is one of the greatest problems facing people across the U.S., and the School of Nursing Health Equity Faculty Fellows program is designed to fight it. “I am confident that the work of our Faculty Fellows will both find solutions and inspire further research that addresses the very real issues faced by our communities,” Dean Pamela R. Jeffries said. This year’s cohort of six scholars, and their research projects, were announced late last month. Read More

Advanced melanoma can be notoriously resistant to standard immunotherapy, but a new drug combination might hold some hope for patients with this most common form of skin cancer. Professor Emerita of Pharmacology Ann Richmond and her team, in preclinical work, created a “tumor microenvironment more receptive to immune challenge.” The treatment slowed tumor growth, showed stronger immune responses and increased helpful T cells. It could be on a faster-than-typical track to human studies because all the drugs are already involved in other clinical trials. Read More

Flying can be a mess that everyone complains about but few people can change. Vanderbilt Law Professor Ganesh Sitaraman might be one of those people. He testified before Congress in early October about what they could do to fix the airline industry: requiring resilience and rainy day funds, setting minimum seat sizes, preventing dynamic pricing and giving passengers the ability to sue. Sitaraman was also a recent guest on Provost C. Cybele Raver’s Quantum Potential podcast, where he talked about his book Why Flying Is Miserable and How To Fix It. Read More

Gastroesophageal reflux disease, or GERD, plagues millions of people. Vanderbilt researchers led by Assistant Professor Xiaoguang Dong have developed a soft robotic valve that can seal off the lower esophagus from the stomach, keeping gastric acid where it belongs. Then when the patient eats or drinks, the valve, which is implanted in concert with a stent, can be opened with a wearable external magnet. “This platform holds promise not only for treating GERD, but also for managing other sphincter-related disorders,” said co-author and Assistant Professor Yuxiao Zhou. Read More

On September 14, 2015, at 4:51 a.m. Central Time, scientists witnessed something no human had ever seen before: two black holes colliding. These black holes, which were 29 and 36 times the mass of the sun, respectively, had been circling each other for millions of years. Their rotations became increasingly faster until they eventually collided and became a single black hole. Since then, scientists have had numerous breakthroughs that deepen our understanding of the universe, and researchers in the College of Arts and Science have been at the forefront, shaping the scientific field of black holes and gravitational waves. Read More

Three leaders in health policy, informatics and cancer research from Vanderbilt University Medical Center have been elected this year to membership in the National Academy of Medicine, a preeminent advisory body on critical matters of health care, medicine and public health. Read More

Political propaganda and artificial intelligence–driven misinformation are infiltrating social media accounts, and Americans need to do something about it. That’s the warning revealed in research from two Vanderbilt professors and discussed on this special episode of the Quantum Potential podcast. Read More

Vanderbilt University may nominate one faculty member in the Chemical Sciences for the Camille Dreyfus Teacher-Scholar Awards Program. Read More

Vanderbilt University may submit one application in either the Institutional Impact or Capacity-Building category to The Educating Character Initiative. Read More

As far back as he can remember, Andy Schwartz has been fascinated by two things—how the brain works and how humans process natural language.   Andy Schwartz, director of the Human Language Analysis Beings lab and research associate professor in the Vanderbilt College of Connected Computing (Submitted photo)… Read More

Andrew Nalani Andrew Nalani, assistant professor of human and organizational development, has joined the Bezos Family Foundation as an inaugural scholar of the Jackie Bezos Researcher in Residence program. Nalani began the one-year residency program on August 18, taking a leave of absence from his faculty position… Read More

Ointments like Neosporin contain the antibiotic neomycin, which works great to kill bacteria on the outside of the body when you scrape your knee or have a hangnail. But inside the body, neomycin does more harm than good—kidney and neurological damage and deafness. Research Assistant Professor Bhawik Jain and colleagues in his lab have figured out why that is, and how to stop it. This could make neomycin another tool in the fight against antibiotic-resistant bacteria. Read More

Much of the human brain is still a mystery, largely because it’s pretty difficult to see what’s going on in there. Assistant Professor Daniel Gonzales and the team in his lab are working to make that easier. They’re using experimental platforms that record brain activity with unprecedented precision on all levels. It works on everything from whole-brain networks to individual synapses—tiny gaps between brain cells that are one-tenth the width of a human hair. “We can … really detail pictures of brain activity during learning,” Gonzales said. “And then we can apply that to study diseases that degrade learning.” Read More

Road closures are a pain—and sometimes they’re not even supposed to be happening. A project by senior research scientist Ayan Mukhopadhyay is working to develop a system—SENTRY—that uses AI to help city inspectors find and address unauthorized road closures in Nashville. “The system has the potential to save millions in unpaid permit fees, reduce external inspection costs and minimize disruptions for residents, commuters and local businesses,” Mukhopadhyay said. His research is supported by a $697,000 grant that's part of NSF's CIVIC Innovation Challenge. Read More