Research

An international team involving Vanderbilt researchers has discovered that a new “checkpoint” protein on immune system cells is active in tumors, and that blocking it — in combination with other treatments — is a successful therapeutic approach in mouse models of cancer. Read More

Frogs don’t like living near noisy highways any better than people do, but research from Vanderbilt suggests that frogs, like hardened city-dwellers, can learn to adapt to the constant din of rumbling trucks, rolling tires and honking horns. Read More

Vanderbilt University Medical Center recently received a $3.9 million grant from the National Institutes of Health to improve outcomes for children with significant hearing loss by providing individualized, prescription-like programming for their cochlear implants. Read More

Drug combinations used for the treatment of non-small-cell lung cancer (NSCLC) and melanoma aren’t as effective as they could be. Oncologists haven’t had the right tools to predict drug interactions, other than in costly clinical trials. That could change with a new algorithm developed by a cross-disciplinary Vanderbilt University team… Read More

Middle Tennessee children with autism spectrum disorder are 2.5 times more likely than children without ASD to be reported to the Child Abuse Hotline by age 8. Read More

Matthew Tyska and colleagues have found that an adhesion protein in the gut is necessary for proper intestinal functioning. Read More

Danny Winder and colleagues have demonstrated how norepinephrine and a stress factor call CRF interact, which may lead to new treatments for stress-related disorders. Read More

Lawrence Marnett and colleagues have demonstrated how two enzymes cooperate to maintain even levels of an important cellular signaling molecule. Read More

Timothy Cover, john Loh and colleagues have identified how a certain type of mutation influences the risk of premalignant and malignant changes in the stomach. Read More

Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders. Read More

Legal immigrants with darker skin are paid up to 25 percent less than those with lighter skin, a wage penalty that widened significantly several years after receiving permanent legal status. Read More

IBM Watson Health has announced plans to make a 10-year, $50 million investment in joint research collaborations with Vanderbilt University Medical Center and Brigham and Women’s Hospital to advance the science of artificial intelligence and its application to major public health issues. Read More

Using sophisticated gene sequencing and computing techniques, Vanderbilt researchers have achieved a first-of-its-kind glimpse into how the body’s immune system gears up to fight off infection. Read More

Even if animals have ulterior motives for teaming up, they teach humans a lot about love, says Vanderbilt University animal biologist Patrick Abbot. Read More

Social media has brought sexual assault into the public eye, but bearing witness to sexual violence in popular culture didn’t begin with the invention of tweets and posts, according to Vanderbilt art history professor Vivien Green Fryd, who explores the topic in her new book. Read More

But long before female-specific medications are available, treatment centers could use the information in this study to educate women about their stronger mental connections to places and objects. Read More

The symposium featured research by students in Vanderbilt's Medical Scholars Program, a one-year, in-depth research experience available to Vanderbilt and Meharry Medical College students with the central goal of training leaders in academic medicine. Read More

Scientists at Vanderbilt's Institute for Software Integrated Systems have developed an award-winning AI to to help triage limited radio frequency demands in real time. Read More

People with blood type B, a relatively rare blood type, can expect similar outcomes from kidney transplants from type A2 donors, which increases the number of available kidneys for these patients. However, it requires additional monitoring and medication that can raise costs for patients. Read More

Craig Brooks and colleagues have identified a mechanism of kidney fibrosis progression, suggesting a potential new angle for treating chronic kidney disease. Read More