Leigh MacMillan
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Study helps define pancreatic cancer’s cellular origins
Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments. Read MoreJan 17, 2013
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Zinc: a new antibiotic target?
It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc. Read MoreJan 17, 2013
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Simulated Mars mission reveals body’s sodium rhythms
Clinical pharmacologist Jens Titze, M.D., and colleagues have discovered that – in contrast to the prevailing dogma – human sodium levels fluctuate rhythmically with 7-day and monthly cycles. Read MoreJan 10, 2013
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Pancreas Center coordinates care for complex cases
Patients with pancreatic diseases can now access a team of multi-disciplinary specialists with one phone call to the new Vanderbilt Pancreas Center. Read MoreJan 10, 2013
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St. Jude’s Schulman first up for 2013 Flexner Discovery Lecture Series
Brenda Schulman, Ph.D., from St. Jude Children’s Research Hospital, kicks off the 2013 Flexner Discovery Lecture series on Thursday, Jan. 10 at 4 p.m. Read MoreJan 4, 2013
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Preventing hardened heart valves
Blocking a serotonin receptor may provide a novel therapy for heart valve disease. Read MoreDec 26, 2012
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A drug combo for ovarian cancer
Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer. Read MoreDec 24, 2012
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Genes, nutrients interact to shape traits
A new study identifies interactions between genes and nutrients that may participate in determining levels of cholesterol and triglycerides. Read MoreDec 12, 2012
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Stanford’s Südhof to discuss how brain relays information
Noted neuroscientist Thomas Südhof, M.D., will deliver the next Flexner Discovery Lecture on Thursday, Dec. 13. Read MoreDec 6, 2012
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‘Longevity’ gene has role in bone loss
A gene associated with long life participates in the normal regulation of bone remodeling and may have a role in bone loss associated with aging. Read MoreDec 6, 2012
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Awards honor diabetes research contributions
The recent “Diabetes Day” symposium recognized two Vanderbilt trainees for their potential as future leaders in diabetes research and one longtime staff member for his service to the diabetes research community. Read MoreNov 29, 2012
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Nobel laureate sheds light on RNA research
There’s been an explosion in the world of RNA — the nucleic acid “copy” of DNA, Nobel laureate Phillip Sharp, Ph.D., told the crowd gathered for his Flexner Discovery Lecture. Read MoreNov 29, 2012
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Rochester’s Maquat set for Flexner Discovery Lecture
Lynne Maquat, Ph.D., the J. Lowell Orbison Endowed Chair and professor of Biochemistry & Biophysics at the University of Rochester, will deliver the next Flexner Discovery Lecture on Thursday, Dec. 6. Read MoreNov 29, 2012
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Polarity protein suppresses tumor growth, invasion
The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model. Read MoreNov 29, 2012
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Green tea for failing hearts?
The main antioxidant compound in green tea increases contractile force in isolated heart cells, suggesting it may be useful in heart failure. Read MoreNov 16, 2012
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Study tracks antioxidants’ role in prostate tumor growth
Antioxidants promote cell growth in a mouse model of prostate cancer, Vanderbilt researchers report in the journal PLoS ONE. The findings provide insight into the recent controversy regarding antioxidants and prostate cancer prevention. Read MoreNov 15, 2012
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Inherited lung disease no worse in offspring
An inherited lung disease does not appear to have earlier onset and increased severity – a phenomenon called genetic anticipation – in successive generations. Read MoreNov 15, 2012
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Nobel laureate Sharp to speak at VUMC
Nobel laureate Phillip Sharp, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, Nov. 15. Read MoreNov 8, 2012
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Symposium to explore diabetes research at VU
“Diabetes at Vanderbilt: From Molecules to People,” a scientific symposium to highlight diabetes research at Vanderbilt, will take place Wednesday, Nov. 14, from 10 a.m. to 2:30 p.m. in the Vanderbilt Student Life Center. Read MoreNov 8, 2012
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Kidney woes during heart failure
Levels of the protein NGAL may be a good predictor of worsening kidney function in patients with acute heart failure. Read MoreNov 8, 2012