Leigh MacMillan

Scott Hultgren, Ph.D., an expert on the interactions between bacteria and human hosts, will deliver the next Flexner Discovery Lecture on Thursday, March 7. Read More

Researchers have found an unusual interaction between a factor that “turns on” protein synthesis and one that produces fatty acids. Read More

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require. Read More

Vanderbilt researchers report that they have found a factor involved in the persistence of embryonic cells implicated in childhood liver cancer. Read More

A protein that connects cells together participates in the calcification that occurs in heart valve disease. Read More

A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm. Read More

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance. Read More

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development. Read More

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart. Read More

In a wide-ranging lecture that moved from plants to nematode worms to human leukemia, Nobel laureate Andrew Fire, Ph.D., outlined his vision for a genomics-based understanding of how organisms respond to novel information. Read More

The kidney can mediate its own repair through proliferation of resident immune system cells. Read More

Structural studies reveal a new framework for understanding a central player in DNA processing. Read More

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk. Read More

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development. Read More

Nobel laureate Andrew Fire, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, Jan. 24. Read More

Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments. Read More

It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc. Read More

Clinical pharmacologist Jens Titze, M.D., and colleagues have discovered that – in contrast to the prevailing dogma – human sodium levels fluctuate rhythmically with 7-day and monthly cycles. Read More

Patients with pancreatic diseases can now access a team of multi-disciplinary specialists with one phone call to the new Vanderbilt Pancreas Center. Read More

Brenda Schulman, Ph.D., from St. Jude Children’s Research Hospital, kicks off the 2013 Flexner Discovery Lecture series on Thursday, Jan. 10 at 4 p.m. Read More