Leigh MacMillan

Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer. Read More

The director of the National Cancer Institute, Harold Varmus, M.D., will deliver the next Flexner Discovery Lecture on Thursday, Nov. 21. His lecture, “New Directions in Cancer Research,” will begin at 4 p.m. in 208 Light Hall. Read More

Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read More

Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles. Read More

Clostridium difficile on the intestinal lining. (Wellcome Images) Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the C. Read More

Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling. Read More

David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes. Read More

Clinicians should be cautious about prescribing newer fluoroquinolone antibiotics to patients with TB risk factors; doing so may jeopardize the use of these agents against TB. Read More

A non-invasive measure of electrical brain activity in preterm infants predicts cognitive and communication functioning during early childhood, according to a new Vanderbilt University study. Read More

Vanderbilt researchers have identified a key regulator of cell division. Read More

A fungus that is killing frogs and other amphibians around the world releases a toxic factor that disables the amphibian immune response, Vanderbilt University investigators report Oct. 18 in the journal Science. Read More

The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance. Read More

Understanding the regulation of mutant EGF receptors commonly found in lung cancers could lead to new targeted therapies. Read More

Keith Yamamoto, Ph.D., an international leader in the study of signaling and gene regulation by intracellular receptors, will deliver the next Flexner Discovery Lecture on Thursday, Oct. 10. Read More

Tony Capra, Ph.D., is a new assistant professor of Biomedical Informatics and investigator in the Center for Human Genetics Research at Vanderbilt. His goal is to use the tools of computer science to address problems in genetics, evolution and biomedicine. Read More

Death of oligodendrocytes, the cells that make myelin, appears to be an early event in the development of multiple sclerosis. Read More

Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay. Read More

A panel of metabolites – small molecules that are part of metabolic processes – that are unique to macular degeneration will shed light on the disease and aid diagnosis. Read More

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer. Read More

We’re on a potential collision course, said last week’s Flexner Discovery Lecturer, between the delivery of good medical care and the possibilities offered by genome medicine. Read More