Leigh MacMillan

Dynamic measurements of the bacterial leucine transporter shed light on the transporters that play roles in neuropsychiatric and addiction disorders. Read More

Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens. Read More

Vanderbilt researchers have identified a new signaling system that anthrax bacteria uses to infect its host. Read More

A protein in the myelin coating on nerves helps form a “seal” that enables effective nerve conduction; loss of the protein causes inherited neuropathies. Read More

Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response. Read More

Vanderbilt investigators have used two types of neuroimaging to establish a “map” of connections for a brain region important in anxiety and addiction. Read More

Neuroscientist and biophysicist David Clapham, M.D., Ph.D., known for his studies of ion channels and cell signaling, will deliver the next Flexner Discovery Lecture on Thursday, April 3, in 208 Light Hall. Read More

A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found. Read More

Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge. Read More

An ion channel protein called TRIPV1 helps retinal neurons survive the elevated eye pressure associated with glaucoma. Read More

Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way. Read More

Blake Wilson, D.Sc., a pioneer in the development of cochlear implants and co-director of the Duke Hearing Center, will deliver the next Flexner Discovery Lecture on Thursday, March 13. Read More

Targeting the enzyme FosB could make antibiotic-resistant staph bacteria sensitive to the antibiotic fosfomycin. Read More

Using imaging data, Vanderbilt researchers discovered an association between a gene pair and brain changes in Alzheimer’s disease. Read More

A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia. Read More

Russ Altman, M.D., Ph.D., professor of Bioengineering, Genetics and Medicine at Stanford University, posed an intriguing question at last week’s Discovery Lecture: is it possible to predict drug side effects from the 3D-structure of proteins? Read More

Neuroscientist Karl Deisseroth, M.D., Ph.D., renowned for his development of tools that allow scientists to control and map brain circuits, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 22. Read More

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity. Read More

Variation in the gene for the beta-1 adrenergic receptor increases the risk that a patient will have an abnormal heart rhythm after cardiac surgery. Read More

Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer. Read More