structural biology
Vanderbilt researchers develop publicly available COVID-19 animal susceptibility prediction tool; suggests increased risk to horses
Oct. 6, 2020—All-remote collaboration results in free animal susceptibility tool to help prioritize research and closer examination of at-risk species.
Assembling cell power plant machinery
Sep. 3, 2020—Tina Iverson and colleagues provide a structural view into the assembly of a protein machine essential for cellular energy production.
A key to calcium signaling
Feb. 11, 2020—Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.
Structural views of a C. diff toxin
Jan. 10, 2020—D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.
Blueprint for treating epilepsy
Nov. 14, 2019—Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders.
Long QT syndrome – revealed
Mar. 12, 2018—Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.
Protein structure may aid in treating Alzheimer’s disease
Apr. 27, 2017—A new protein structure may guide the development of Alzheimer's therapeutics.
Fighting fungal infections
Apr. 3, 2017—A detailed structural and functional analysis of the yeast protein that is the main target of antifungal drugs will help direct efforts to develop better treatments.
Chemist Jens Meiler receives Humboldt Foundation award
Dec. 15, 2015—Associate Professor of Chemistry Jens Meiler has received a Friedrich Wilhelm Bessel Research Award from the Alexander von Humboldt Foundation in Bonn, Germany.
Bacterial secretion machinery: 3-D view
Dec. 11, 2014—New structural findings reveal how "gatekeeper" proteins participate in the secretion systems bacteria use to infect host cells.
New view of transporter dynamics
Oct. 23, 2014—New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants.
How ABC transporters move molecules
Jun. 13, 2014—New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis.