Serotonin

Using sophisticated genome mining and gene manipulation techniques, researchers at Vanderbilt University Medical Center (VUMC) have solved a mystery that could lead to a new treatment approach for autism spectrum disorder (ASD). Read More

The duration of exposure to daylight, or the “photoperiod,” may affect development of seasonal affective disorder by programming serotonin neurons in the brain, according to Vanderbilt University researchers. Read More

The 2C-subtype of the serotonin receptor (5HT2C), which binds the neurotransmitter serotonin, plays an important role in regulating food intake and metabolism. Read More

Vanderbilt researchers have established a link between the neurotransmitter serotonin and certain behaviors of some children with autism spectrum disorder (ASD), a link that may lead to new treatments for ASD. Read More

Vanderbilt University scientists are a step closer to understanding how inflammation in the body can affect mood and behavior. Read More

A compound acting on serotonin receptors delays a critical step during reovirus cell entry, reducing viral infectivity. Read More

Blocking a serotonin receptor may provide a novel therapy for heart valve disease. Read More

A combination of biomarkers may reveal new clues about causes of and potential interventions for autism. Read More

An interdisciplinary team of scientists have successfully tagged a protein that regulates the neurotransmitter serotonin with tiny fluorescent beads, allowing them to track the movements of individual molecules for the first time. This capability makes it possible to study the manner in which serotonin regulates mood, appetite and sleep at a new level of detail. Read More

A genetic variation that causes early disruptions in serotonin signaling in the brain may contribute to autism spectrum disorder and other enduring effects on behavior. Read More

The Vanderbilt MRI Labs Physics / Imaging Department (Anne Rayner / Vanderbilt) Serotonin – a chemical that has roles in multiple brain functions, including mood, sleep and cognition – is manufactured by clusters of brainstem neurons gathered in the raphé nuclei. A reliable, non-invasive imaging method for assessing raphé neuron… Read More