Sean Davies

Sean Davies, associate professor of pharmacology and associate director of graduate studies for the department, has been awarded a Scaling Success grant from Research Development and Support in the Office of the Vice Provost for Research and Innovation. Read More

Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins. Read More

A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center. Read More

Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction. Read More

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis. Read More

Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases. Read More

Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read More

An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain. Read More

Sean Davies, Ph.D., associate professor of Pharmacology, was recognized as Pharmacology “Teacher of the Year” during the 25th Annual Joel G. Hardman Student-Invited Pharmacology Forum in Light Hall. Read More

High-density lipoprotein (HDL) is known as “good cholesterol” because elevated levels protect against heart attacks and plaque buildup. However, in some cases HDL may not function properly and may actually accelerate the disease. Read More

Private Property and Government Inaction | Probiotic Could Prevent Obesity | Freedom from Power Cords | Pickiness Doesn’t Always Pay Read More

In some cases, HDL, the "good cholesterol," may not function properly and may actually accelerate atherosclerosis. Read More

Engineered bacteria that produce a therapeutic compound in the gut prevent obesity in mice, Vanderbilt University investigators have discovered. Read More