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Science Advances Archives

Long QT syndrome – revealed

Mar. 12, 2018—Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.

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Discovery sheds light on protein key to nerve cells’ myelin sheath

Aug. 17, 2017—Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear.

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Northern coast of Peru was a hospitable rest stop for early Americans

May. 24, 2017—Vanderbilt researchers found a place where early Americans paused on their migrations south and "settled in for a good long while," suggesting a slower pace of settlement than originally believed.

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Protein structure may aid in treating Alzheimer’s disease

Apr. 27, 2017—A new protein structure may guide the development of Alzheimer's therapeutics.

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Study reveals new clues to cystic fibrosis ‘gender gap’

Sep. 15, 2016—A research team led by structural biologists from Vanderbilt University has come up with the first detailed molecular explanation for a factor that may contribute to the so-called cystic fibrosis (CF) “gender gap.”

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