School Of Medicine

Vanderbilt University researchers have discovered how a protein pump distinguishes between chemicals that it will expel from a cell and inhibitors that block its action. The new findings could guide the development of more efficient inhibitors to prevent cancer cell resistance to chemotherapy. Read More

Gary H. Cheek, a retired U.S. Army lieutenant general, joined Vanderbilt in April to direct the newly created Bass Military Scholars Program, established in 2018 with a $25 million gift from the Lee and Ramona Bass Foundation. Read More

The flu mutates so quickly that we need a new vaccine every year, but Vanderbilt scientists have found a vulnerable part of the virus that doesn't mutate as much. Read More

Louise Rollins-Smith and colleagues have discovered a new way that a deadly fungus evades frogs' immune systems. Read More

Basement membranes are important structural and functional components of tissues. New research provides insight into how they repair themselves. Read More

New findings may speed progress toward programming cells to rebuild damaged hearts more quickly. Read More

Benign lesions caused by a common fungus can mimic those caused by cancer in the lungs. A Vanderbilt research team is on the hunt for a non-invasive way for doctors to tell the two diseases apart. Read More

Asian countries are in the early stages of a tobacco smoking epidemic with habits mirroring those of the United States from past decades, setting the stage for a spike in future deaths from smoking-related diseases. Read More

Using a unique computational framework they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute has identified 104 high-risk genes for schizophrenia. Read More

Eric Skaar and colleagues have figured out how a common bug responsible for ventilator-associated pneumonia responds when starved of zinc, a metal it needs to survive, which may lead to new therapeutic targets for the dangerous infection. Read More

A report by researchers at Vanderbilt University Medical Center has shattered conventional wisdom about how cells, including cancer cells, shed DNA into the bloodstream. Read More

Jonathan Schoenecker, Stephanie Moore-Lotridge and colleagues have found a new target for treating a condition that causes bone to form in soft tissue, reducing mobility. Read More

Austin Kirschner and colleagues are learning more about how the cancer drug enzalutamide combines with radiation therapy to treat difficult prostate tumors. Read More

A commonly used muscle relaxant can cause severely low blood pressure in patients already taking a CYP1A2 inhibitor, such as ciprofloxacin, find Cecilia Chung and colleagues. Read More

Jonathan Soslow and colleagues have found more clues to why people with Duchenne muscular dystrophy are at risk for a certain kind of heart problem. Read More

Stephen Fesik and colleagues have uncovered more details about how a crucial component of RAS proteins, which trigger about a third of all tumors, work. This finding will help advance the discovery of new cancer therapies. Read More

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered. Read More

VUMC has received significant grants to study pulmonary fibrosis, a progressive and irreversible disease characterized by shortness of breath and a dry cough. Read More

Jason McGurn and colleagues have uncovered new insights into the complex and highly coordinated endocytic trafficking mechanism, which is an essential part of many cellular processes including sodium resorption by the kidney and regulation of blood plasma sodium levels. Read More

A $3.4 million grant from the National Institute of Mental Health will fund Vanderbilt research on treatment resistance in patients with major depressive disorder and schizophrenia. Read More