School Of Medicine Basic Sciences
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Enzyme helps build motor that drives neuron death
The process, discovered in the axons of neurons, is implicated in Alzheimer’s, amyotrophic lateral sclerosis, traumatic brain injury and other diseases or injuries to the nervous system. Read MoreAug 6, 2018
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Three VU doctoral students receive 2018 Gilliam Fellowships for Advanced Study
The Howard Hughes Medical Institute has awarded 2018 Gilliam Fellowships for Advanced Study—created to ensure that a diverse and highly trained workforce is prepared to assume leadership roles in the sciences—to three Vanderbilt University doctoral students and their advisers. Read MoreAug 1, 2018
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Fueling the MATE transporter
In new research, Hassane Mchaourab and colleagues have uncovered new insights into drug resistance that could lead to the development of new anti-cancer and antibacterial drugs. Read MoreJul 20, 2018
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SMAD4 clue to colon cancer
Chronic inflammation is a predisposing condition for colorectal cancer, the third leading cause of cancer-related deaths in the United States. Anna Means, Ph.D., and colleagues have now linked inflammation-driven carcinogenesis in the colon to loss of an important signaling protein called SMAD4. Read MoreJul 5, 2018
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Scavengers “protect” HDL
Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read MoreJun 29, 2018
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Roden’s circulatory diseases research honored
Vanderbilt University’s Dan Roden, MD, internationally known for his contributions to understanding how genetic variation affects drug response, has been named a recipient of the 2018 Louis and Artur Lucian Award for Research in Circulatory Diseases by McGill University in Montreal, Canada. Read MoreJun 21, 2018
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Confronting TB resistance
Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis. Read MoreJun 11, 2018
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$8.1 million grant funds new center to research highly aggressive form of lung cancer
A five-year National Cancer Institute grant will fund an interdisciplinary research center for the study of small cell lung cancer, a highly aggressive, incurable form of the disease. Read MoreJun 8, 2018
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Enzyme protects against obesity-related heart disease
Vanderbilt scientists have discovered that a certain enzyme plays a crucial role in preventing obesity-related cardiac dysfunction. Read MoreJun 7, 2018
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View ‘Report on Sexual Harassment of Women’ webinar June 12
Join your Vanderbilt colleagues in viewing a webinar on the public release of a new report, “Sexual Harassment of Women: Climate, Culture and Consequences in Academic Sciences, Engineering and Medicine.” Read MoreMay 30, 2018
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Seven interdisciplinary programs land TIPs awards for 2018
Vanderbilt University’s transformational Trans-Institutional Programs initiative heads into a fourth year with grants awarded to seven interdisciplinary projects that involve more than 60 faculty members. Read MoreMay 24, 2018
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Shaping reward circuits
Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry. Read MoreMay 18, 2018
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Looking beyond the ‘magic bullet’ approach to drug discovery
Vanderbilt scientists have developed a new process that can rapidly and inexpensively identify personalized cancer drugs derived from nature. Read MoreMay 1, 2018
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Toxin floats on lipid rafts
The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read MoreApr 23, 2018
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Ancora inaugural request for proposals announced
The Office of the Vice Provost for Research and Deerfield Management announce the inaugural request for proposals for Ancora Innovation, LLC, with a due date of June 4. An RFP information session is scheduled from 2 to 3:30 p.m. Friday, April 27, at Sarratt Student Center, Room 325. Read MoreApr 20, 2018
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How the skin protects
Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier. Read MoreApr 19, 2018
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Characterizing ‘keyhole’ is first step to fighting obesity at the cellular level
A Vanderbilt team and their international colleagues characterized for the first time a complex, little-understood cellular receptor type that, when activated, shuts off hunger. Read MoreApr 18, 2018
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“Idling” cancer cells may return
Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment. Read MoreApr 11, 2018
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New view of the heartbeat
Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias. Read MoreApr 6, 2018
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‘Collaborating with industry to advance basic science research’ topic of April 6 talk
The Center for Technology Transfer and Commercialization's Alan Bentley will discuss emerging initiatives at Vanderbilt to engage industry more effectively, and a team from Deerfield Management will explain its collaborative approach to working with premier academic institutions to catalyze early stage therapeutic development. Read MoreApr 4, 2018