Research
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Potential schizophrenia treatment, discovered at Vanderbilt and being developed by Neumora Therapeutics, entering Phase 1 clinical trial
In just over two years, a Vanderbilt-Neumora collaboration has led to the Phase 1 clinical trial of a treatment for schizophrenia spectrum disorders, which affect 3.7 million adults in the United States. This is the third chemical compound discovered at the Warren Center for Neuroscience Drug Discovery to reach Phase 1 clinical trials. Read MoreDec 4, 2023
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Study links gene network and pancreatic beta cell defects to Type 2 diabetes
A comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to Type 2 diabetes. Read MoreDec 4, 2023
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Nonprofits support quest to cure childhood epilepsy
Monica Joanna Elnekaveh was doing everything she could to learn what was causing her 18-month-old daughter’s developmental issues. Her relentless quest to find answers eventually led her to Vanderbilt investigative neurologist Jing-Qiong (Katty) Kang, MD, PhD. Read MoreNov 29, 2023
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VUMC scientists discover key step to kidney fibrosis
Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure. Read MoreNov 21, 2023
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Vanderbilt named spoke in ARPA-H Investor Catalyst Hub
Vanderbilt University has been selected as an inaugural spoke for the ARPA-H Investor Catalyst Hub, a crucial component of the ARPANET-H initiative aimed at advancing accessible biomedical innovations. This partnership positions Vanderbilt to access potential funding and networking opportunities and provide input into ARPA-H’s health care research focus areas, aligning with their mission to accelerate equitable health care solutions nationwide. Read MoreNov 20, 2023
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Tumor antigens key to improving cancer immunotherapy: study
Vanderbilt researchers are working to better design immune therapies that attack tumors without also attacking healthy normal tissue in patients. Read MoreNov 17, 2023
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Twelve at Vanderbilt are among world’s highly cited researchers
Twelve current investigators at Vanderbilt University Medical Center and Vanderbilt University are on this year’s list of scientists whose papers have been cited the most frequently by other researchers. Read MoreNov 15, 2023
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Novel C. diff structures are required for infection, offer new therapeutic targets
Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs. Read MoreNov 15, 2023
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Next-gen air safety systems incorporating risk models and data analysis developed by Vanderbilt engineers
by Brenda Ellis As the nation’s skies become more crowded with commercial air traffic and U.S. air traffic control systems struggle with staffing and aging infrastructure, the risk of narrowly avoided collisions in the air and on the tarmac has increased significantly in the last five years. The nation’s top accident investigator said that a... Read MoreNov 15, 2023
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Vanderbilt’s Abhishek Dubey leads symposium on sustainable cities research
Abhishek Dubey, associate professor of computer science and electrical and computer engineering, is leading a one-day symposium on Nov. 13 at Cornell Tech highlighting innovative research for sustainable cities. Called Urban Tech Academy day, the event sponsored by the National Science Foundation and Cornell Tech will focus on “clean electrified multimodal transportation systems.” Over two... Read MoreNov 13, 2023
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Most can lower blood pressure by reducing salt, even those on BP drugs: study
New research shows nearly everyone can lower their blood pressure, even people currently on blood pressure- reducing drugs, by lowering their sodium intake. Read MoreNov 13, 2023
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Researchers’ breakthrough in thermal transport could enable novel cooling strategies
Vanderbilt mechanical engineering professors Deyu Li and Josh Caldwell are part of a team of researchers who have discovered a new heat dissipation channel using phonon polaritons that could have extensive implications for novel cooling technologies in devices like smart phones and other modern electronics. The research was recently published in Nature Communications under the... Read MoreNov 10, 2023
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Children’s antibodies highly potent against COVID-19: study
Reporting Nov. 6 in Cell Reports Medicine, Ivelin Georgiev, PhD, and colleagues demonstrated that antibodies isolated from children’s blood samples displayed high levels of neutralization and potency against variants of the COVID-19 virus, SARS-CoV-2, even when the children had not previously been exposed to or vaccinated against those variants. Read MoreNov 6, 2023
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Pancreas “crosstalk” may influence course of Type 1 and Type 2 diabetes
In the largest study of its kind, researchers at Vanderbilt have identified unexpected alterations in the exocrine tissues of the pancreas that occur in the two major forms of diabetes, and with aging and obesity. Read MoreNov 1, 2023
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Osheroff receives Distinguished Teacher Award from Association of American Medical Colleges
As a professor of biochemistry and medicine at Vanderbilt University School of Medicine for more than 40 years, Osheroff is the longest serving course director currently teaching medical students. He also codirects the preclerkship phase of the medical school curriculum and leads the Master Science Teachers cohort, a role established in 2007 to recognize VUSM’s outstanding basic science educators. Through his teaching, he has helped medical students at VUSM and across the globe acquire the basic science skills and knowledge they need to thrive in clinical practice, according to the AAMC. Read MoreOct 31, 2023
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Crowe, Osheroff honored by AAMC
Vanderbilt's James E. Crowe, Jr, MD, and Neil Osheroff, PhD, are among 12 individuals honored by the Association of American Medical Colleges during its 2023 Awards Recognition Event. Read MoreOct 30, 2023
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Study discovers role for gut bacteria in host-pathogen competition for nutrients
Vanderbilt research shows that commensal gut microbes impact the host-pathogen competition for iron and have implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients. Read MoreOct 27, 2023
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Biochemist Martin Egli elected to the European Academy of Sciences and Arts
For his outstanding achievements, including investigations directed at nucleic acid structure, DNA bypass polymerases and the circadian clock, Martin Egli has been elected to the European Academy of Sciences and Arts. The academy is dedicated to innovative research, interdisciplinary and transnational collaboration. Read MoreOct 25, 2023
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Biomedical Ph.D. alumni career goals and outcomes revealed in new research
New research from the Office of Biomedical Research Education and Training connects the dots between career goals during graduate school and career outcomes, articulates how careers of Ph.D. alumni evolve during the 10 years after graduation. Read MoreOct 24, 2023
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Vanderbilt-led team receives 2023 Endeavor Award from The Mark Foundation for Cancer Research
A multidisciplinary team of investigators has received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to support four closely linked projects exploring the fundamental mechanisms that drive the obesity-cancer connection, Read MoreOct 24, 2023